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Cancers|February 15, 2022
A Polytherapy Strategy Using Vincristine and ALK Inhibitors to Sensitise EML4-ALK-Positive NSCLCJosephina Sampson, Hyun-Min Ju, Ji-Young Song, et al.European Journal of Cancer (Oxford, England : 1990)|November 8, 2025
Molecular and Clinical characteristics of ROS1 Fusion Variants in ROS1-rearranged Cancers: A Defined Role of Fusion Partners and Breakpoints of ROS1Ji-Seon Jeong, Yeokyeong Shin, Shinkyo Yoon, et al.Chemical Science|December 2, 2024
Constrained TACC3 peptidomimetics for a non-canonical protein-protein interface elucidate allosteric communication in Aurora-A kinaseDiana Gimenez, Martin Walko, Jennifer A Miles, et al.Open Biology|July 15, 2016
Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domainSelena G Burgess, Arkadiusz Oleksy, Tommaso Cavazza, et al.The EMBO Journal|June 18, 2002
Structural basis for the interaction between NTF2 and nucleoporin FxFG repeatsRichard Bayliss, Sara W Leung, Rosanna P Baker, et al.Journal of Molecular Biology|November 21, 2009
A pocket on the surface of the N-terminal BRCT domain of Mcph1 is required to prevent abnormal chromosome condensationMark W Richards, Justin W C Leung, S Mark Roe, et al.Proceedings of the National Academy of Sciences of the United States of America|May 2, 2006
Dimerization and interactions of Brucella suis VirB8 with VirB4 and VirB10 are required for its biological activityAthanasios Paschos, Gilles Patey, Durga Sivanesan, et al.Proceedings of the National Academy of Sciences of the United States of America|November 13, 2016
Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitorsMark W Richards, Selena G Burgess, Evon Poon, et al.Bioorganic & Medicinal Chemistry|May 17, 2018
Synthesis and profiling of a 3-aminopyridin-2-one-based kinase targeted fragment library: Identification of 3-amino-5-(pyridin-4-yl)pyridin-2(1H)-one scaffold for monopolar spindle 1 (MPS1) and Aurora kinases inhibitionDaren Fearon, Isaac M Westwood, Rob L M van Montfort, et al.The Biochemical Journal|January 14, 2010
Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug designCharlotte A Dodson, Magda Kosmopoulou, Mark W Richards, et al.Pageof 13