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Thrombosis Research|January 7, 2010
The R306G and R506Q mutations in coagulation Factor V reveals additional cleavage sites for Activated Protein C in the R313-R321 region and at R505Richard J Dirven, Hans L Vos, Rogier M Bertina
Plos One|June 14, 2023
Automated segmentation and quantitative analysis of organelle morphology, localization and content using CellProfilerSebastiaan N J Laan, Richard J Dirven, Petra E Bürgisser, et al.
Thrombosis and Haemostasis|March 8, 2003
The R2-haplotype associated Asp2194Gly mutation in the light chain of human factor V results in lower expression levels of FV, but has no influence on the glycosylation of Asn2181Marijn van der Neut Kolfschoten, Richard J Dirven, Hans L Vos, et al.
The Journal of Biological Chemistry|December 9, 2003
Factor Va is inactivated by activated protein C in the absence of cleavage sites at Arg-306, Arg-506, and Arg-679Marijn van der Neut Kolfschoten, Richard J Dirven, Hans L Vos, et al.
Haematologica|December 31, 2011
Biogenesis of Weibel-Palade bodies in von Willebrand's disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formationJiong-Wei Wang, Dafna J Groeneveld, Guy Cosemans, et al.
Journal of Thrombosis and Haemostasis : JTH|April 4, 2024
Transcriptional and functional profiling identifies inflammation and endothelial-to-mesenchymal transition as potential drivers for phenotypic heterogeneity within a cohort of endothelial colony forming cellsSebastiaan N J Laan, Suzan de Boer, Richard J Dirven, et al.
British Journal of Haematology|August 9, 2014
Storage and secretion of naturally occurring von Willebrand factor A domain variantsDafna J Groeneveld, Jiong-Wei Wang, Marjon J Mourik, et al.
Thrombosis and Haemostasis|August 18, 2020
Ex vivo Improvement of a von Willebrand Disease Type 2A Phenotype Using an Allele-Specific Small-Interfering RNAAnnika de Jong, Richard J Dirven, Johan Boender, et al.
Blood|January 26, 2013
VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand diseaseJeroen Eikenboom, Augusto B Federici, Richard J Dirven, et al.
The Journal of Biological Chemistry|May 21, 2011
Intracellular storage and regulated secretion of von Willebrand factor in quantitative von Willebrand diseaseJiong-Wei Wang, Karine M Valentijn, Hetty C de Boer, et al.
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