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Richard LeDuc

Showing results (121-130 of 136) with videos related to

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Antiviral Research|March 28, 2024
Nanomolar anti-SARS-CoV-2 Omicron activity of the host-directed TMPRSS2 inhibitor N-0385 and synergistic action with direct-acting antiviralsJimena Pérez-Vargas, Gabriel Lemieux, Connor A H Thompson, et al.
Arthritis & Rheumatology (Hoboken, N.J.)|May 3, 2017
Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple MechanismsDavid J Wilkinson, Hui Wang, Angela Habgood, et al.
Science Signaling|December 6, 2018
Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensorsYoon Namkung, Christian LeGouill, Sahil Kumar, et al.
Arthritis and Rheumatism|May 28, 2010
Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritisJennifer M Milner, Amit Patel, Rose K Davidson, et al.
The Journal of Clinical Investigation|February 18, 2014
Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive propertiesMichel Demeule, Nicolas Beaudet, Anthony Régina, et al.
Cell Chemical Biology|September 24, 2019
Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human HepatocytesFrançois Béliveau, Aarti Tarkar, Sébastien P Dion, et al.
Nature Communications|September 28, 2024
The urotensin II receptor triggers an early meningeal response and a delayed macrophage-dependent vasospasm after subarachnoid hemorrhage in male miceMartin Pedard, Lucie Prevost, Camille Carpena, et al.
Journal of Medicinal Chemistry|March 31, 2025
From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 VariantsGabriel Lemieux, Jimena Pérez-Vargas, Antoine Désilets, et al.
Nature Communications|May 10, 2025
Structural basis of TMPRSS11D specificity and autocleavage activationBryan J Fraser, Ryan P Wilson, Sára Ferková, et al.
Scientific Reports|December 3, 2017
The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnoverDavid J Wilkinson, Antoine Desilets, Hua Lin, et al.
Pageof 14

Showing results (121-130 of 136) with videos related to

Sort By:
Pageof 14
Antiviral Research|March 28, 2024
Nanomolar anti-SARS-CoV-2 Omicron activity of the host-directed TMPRSS2 inhibitor N-0385 and synergistic action with direct-acting antiviralsJimena Pérez-Vargas, Gabriel Lemieux, Connor A H Thompson, et al.
Arthritis & Rheumatology (Hoboken, N.J.)|May 3, 2017
Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple MechanismsDavid J Wilkinson, Hui Wang, Angela Habgood, et al.
Science Signaling|December 6, 2018
Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensorsYoon Namkung, Christian LeGouill, Sahil Kumar, et al.
Arthritis and Rheumatism|May 28, 2010
Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritisJennifer M Milner, Amit Patel, Rose K Davidson, et al.
The Journal of Clinical Investigation|February 18, 2014
Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive propertiesMichel Demeule, Nicolas Beaudet, Anthony Régina, et al.
Cell Chemical Biology|September 24, 2019
Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human HepatocytesFrançois Béliveau, Aarti Tarkar, Sébastien P Dion, et al.
Nature Communications|September 28, 2024
The urotensin II receptor triggers an early meningeal response and a delayed macrophage-dependent vasospasm after subarachnoid hemorrhage in male miceMartin Pedard, Lucie Prevost, Camille Carpena, et al.
Journal of Medicinal Chemistry|March 31, 2025
From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 VariantsGabriel Lemieux, Jimena Pérez-Vargas, Antoine Désilets, et al.
Nature Communications|May 10, 2025
Structural basis of TMPRSS11D specificity and autocleavage activationBryan J Fraser, Ryan P Wilson, Sára Ferková, et al.
Scientific Reports|December 3, 2017
The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnoverDavid J Wilkinson, Antoine Desilets, Hua Lin, et al.
Pageof 14