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Cell|August 30, 2014
Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transitionYoav D Shaul, Elizaveta Freinkman, William C Comb, et al.Molecular Cell|November 5, 2020
Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase εVladislav O Sviderskiy, Lili Blumenberg, Elizabeth Gorodetsky, et al.Cell|July 3, 2020
Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic RedundancyLin Wu, Kate E R Hollinshead, Yuhan Hao, et al.Cancer Discovery|July 30, 2025
Mitochondrial glutathione import enables breast cancer metastasis via integrated stress response signalingHsi-Wen Yeh, Nicole Lauren DelGaudio, Beste Uygur, et al.Nature|December 13, 2019
KRAS4A directly regulates hexokinase 1Caroline R Amendola, James P Mahaffey, Seth J Parker, et al.Science Advances|July 17, 2026
Iron overload suppresses LKB1 and induces IL36G anti-tumor immunity in PDAC metastasisDouglas E Biancur, Harsha Venkatesh, Amy Crawford, et al.Elife|October 3, 2017
Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancerVolkan I Sayin, Sarah E LeBoeuf, Simranjit X Singh, et al.Cancer Research|July 11, 2020
Epigenetic CRISPR Screens Identify Npm1 as a Therapeutic Vulnerability in Non-Small Cell Lung CancerFei Li, Wai-Lung Ng, Troy A Luster, et al.Nature|July 16, 2011
Functional genomics reveal that the serine synthesis pathway is essential in breast cancerRichard Possemato, Kevin M Marks, Yoav D Shaul, et al.Cell Reports|November 8, 2023
The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerabilityNiklas Ravn-Boess, Nainita Roy, Takamitsu Hattori, et al.Pageof 5