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The Journal of Biological Chemistry|August 8, 2009
The signature 3-O-sulfo group of the anticoagulant heparin sequence is critical for heparin binding to antithrombin but is not required for allosteric activationBenjamin Richard, Richard Swanson, Steven T OlsonBlood|December 7, 2011
Specificity and selectivity profile of EP217609: a new neutralizable dual-action anticoagulant that targets thrombin and factor XaSteven T Olson, Richard Swanson, Maurice PetitouThe Journal of Biological Chemistry|May 13, 2022
Heparin activation of protein Z-dependent protease inhibitor (ZPI) allosterically blocks protein Z activation through an extended heparin-binding siteXin Huang, Richard Swanson, Steven T OlsonArteriosclerosis, Thrombosis, and Vascular Biology|February 20, 2025
Tapping Into the Natural PZ-Independent Anticoagulant Function of ZPI to Inhibit Thrombosis With Minimal Effect on HemostasisXin Huang, Richard Swanson, Can Wang, et al.Biochemistry|March 22, 2018
Cooperative Interactions of Three Hotspot Heparin Binding Residues Are Critical for Allosteric Activation of Antithrombin by HeparinBenjamin Richard, Richard Swanson, Gonzalo Izaguirre, et al.The Journal of Biological Chemistry|March 29, 2019
Protein Z-dependent protease inhibitor (ZPI) is a physiologically significant inhibitor of prothrombinase functionXin Huang, Richard Swanson, Heather K Kroh, et al.The Journal of Biological Chemistry|September 5, 2008
Kinetic characterization of the protein Z-dependent protease inhibitor reaction with blood coagulation factor XaXin Huang, Richard Swanson, George J Broze, et al.The Journal of Biological Chemistry|October 9, 2003
Localization of an antithrombin exosite that promotes rapid inhibition of factors Xa and IXa dependent on heparin activation of the serpinGonzalo Izaguirre, Weiqing Zhang, Richard Swanson, et al.The Journal of Biological Chemistry|October 17, 2006
Antiangiogenic antithrombin blocks the heparan sulfate-dependent binding of proangiogenic growth factors to their endothelial cell receptors: evidence for differential binding of antiangiogenic and anticoagulant forms of antithrombin to proangiogenic heparan sulfate domainsWeiqing Zhang, Richard Swanson, Yan Xiong, et al.Biochemistry|April 6, 2021
Paramount Importance of Core Conformational Changes for Heparin Allosteric Activation of AntithrombinGonzalo Izaguirre, Richard Swanson, Ryan Roth, et al.Pageof 4