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Bioorganic & Medicinal Chemistry Letters|February 3, 2012
Novel morpholine ketone analogs as potent histamine H3 receptor inverse agonists with wake activityBabu G Sundar, Thomas R Bailey, Derek Dunn, et al.Bioorganic & Medicinal Chemistry Letters|February 1, 2012
4-phenoxypiperidine pyridazin-3-one histamine H(3) receptor inverse agonists demonstrating potent and robust wake promoting activityRobert L Hudkins, Allison L Zulli, Reddeppa reddy Dandu, et al.Journal of Medicinal Chemistry|June 4, 2011
Discovery and characterization of 6-{4-[3-(R)-2-methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, irdabisant): a potent, selective histamine H3 receptor inverse agonistRobert L Hudkins, Rita Raddatz, Ming Tao, et al.The Journal of Pharmacology and Experimental Therapeutics|October 18, 2011
CEP-26401 (irdabisant), a potent and selective histamine H₃ receptor antagonist/inverse agonist with cognition-enhancing and wake-promoting activitiesRita Raddatz, Robert L Hudkins, Joanne R Mathiasen, et al.Bioorganic & Medicinal Chemistry Letters|July 26, 2011
Identification of pyridazin-3-one derivatives as potent, selective histamine H₃ receptor inverse agonists with robust wake activityRobert L Hudkins, Lisa D Aimone, Thomas R Bailey, et al.Pageof 3