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The Journal of Biological Chemistry
|
July 12, 2005
The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity
Andrea D Basso, Asra Mirza, Gongjie Liu, et al.
Cureus
|
November 17, 2025
Implementation of a Novel, Intensive, Two-Week Simulation Rotation for Pediatric Residents to Teach Crisis Resource Management Skills
Lorel R Huber, Robert Bishop, Shannon M Flood, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 27, 2004
Farnesyl protein transferase inhibitors targeting the catalytic zinc for enhanced binding
F George Njoroge, Bancha Vibulbhan, Patrick Pinto, et al.
Experimental Cell Research
|
February 2, 2002
Inhibitors of farnesyl protein transferase and MEK1,2 induce apoptosis in fibroblasts transformed with farnesylated but not geranylgeranylated H-Ras
Diana L Brassard, Jessie M English, Michael Malkowski, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 22, 2005
Enhanced FTase activity achieved via piperazine interaction with catalytic zinc
F George Njoroge, Bancha Vibulbhan, Patrick Pinto, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 27, 2004
Bridgehead modification of trihalocycloheptabenzopyridine leads to a potent farnesyl protein transferase inhibitor with improved oral metabolic stability
F George Njoroge, Bancha Vibulbhan, Xiongwei Shi, et al.
Advances in Anesthesia
|
January 22, 2024
Reconceptualizing Acute Pain Management in the 21st Century
Stephen Macres, Robin J Aldwinckle, Usha Saldahna, et al.
International Journal of Cancer
|
June 17, 2009
Continuous and intermittent dosing of lonafarnib potentiates the therapeutic efficacy of docetaxel on preclinical human prostate cancer models
Gongjie Liu, Stacey A Taylor, Cindy H Marrinan, et al.
Bioorganic & Medicinal Chemistry
|
December 7, 2002
Trihalobenzocycloheptapyridine analogues of Sch 66336 as potent inhibitors of farnesyl protein transferase
F George Njoroge, Bancha Vibulbhan, Patrick Pinto, et al.
Gynecologic Oncology
|
February 2, 2008
Combining the farnesyltransferase inhibitor lonafarnib with paclitaxel results in enhanced growth inhibitory effects on human ovarian cancer models in vitro and in vivo
Stacey A Taylor, Cindy H Marrinan, Gongjie Liu, et al.
Page
of 6
Search research articles
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Showing results (11-20 of 53) with videos related to
Sort By:
Page
of 6
The Journal of Biological Chemistry
|
July 12, 2005
The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity
Andrea D Basso, Asra Mirza, Gongjie Liu, et al.
Cureus
|
November 17, 2025
Implementation of a Novel, Intensive, Two-Week Simulation Rotation for Pediatric Residents to Teach Crisis Resource Management Skills
Lorel R Huber, Robert Bishop, Shannon M Flood, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 27, 2004
Farnesyl protein transferase inhibitors targeting the catalytic zinc for enhanced binding
F George Njoroge, Bancha Vibulbhan, Patrick Pinto, et al.
Experimental Cell Research
|
February 2, 2002
Inhibitors of farnesyl protein transferase and MEK1,2 induce apoptosis in fibroblasts transformed with farnesylated but not geranylgeranylated H-Ras
Diana L Brassard, Jessie M English, Michael Malkowski, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 22, 2005
Enhanced FTase activity achieved via piperazine interaction with catalytic zinc
F George Njoroge, Bancha Vibulbhan, Patrick Pinto, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 27, 2004
Bridgehead modification of trihalocycloheptabenzopyridine leads to a potent farnesyl protein transferase inhibitor with improved oral metabolic stability
F George Njoroge, Bancha Vibulbhan, Xiongwei Shi, et al.
Advances in Anesthesia
|
January 22, 2024
Reconceptualizing Acute Pain Management in the 21st Century
Stephen Macres, Robin J Aldwinckle, Usha Saldahna, et al.
International Journal of Cancer
|
June 17, 2009
Continuous and intermittent dosing of lonafarnib potentiates the therapeutic efficacy of docetaxel on preclinical human prostate cancer models
Gongjie Liu, Stacey A Taylor, Cindy H Marrinan, et al.
Bioorganic & Medicinal Chemistry
|
December 7, 2002
Trihalobenzocycloheptapyridine analogues of Sch 66336 as potent inhibitors of farnesyl protein transferase
F George Njoroge, Bancha Vibulbhan, Patrick Pinto, et al.
Gynecologic Oncology
|
February 2, 2008
Combining the farnesyltransferase inhibitor lonafarnib with paclitaxel results in enhanced growth inhibitory effects on human ovarian cancer models in vitro and in vivo
Stacey A Taylor, Cindy H Marrinan, Gongjie Liu, et al.
Page
of 6