Showing results (21-30 of 46) with videos related to
Sort By:
Pageof 5
Bioorganic & Medicinal Chemistry Letters|December 4, 2003
Rational design, synthesis and structure-activity relationships of a cyclic succinate series of TNF-alpha converting enzyme inhibitors. Part 1: lead identificationChu-Biao Xue, Xiaohua He, John Roderick, et al.Biochemical and Biophysical Research Communications|July 7, 2009
Pharmacological characterization of INCB3344, a small molecule antagonist of human CCR2Niu Shin, Frédéric Baribaud, Kathy Wang, et al.Gynecologic Oncology|July 13, 2017
A randomised, open-label, phase 2 study of the IDO1 inhibitor epacadostat (INCB024360) versus tamoxifen as therapy for biochemically recurrent (CA-125 relapse)-only epithelial ovarian cancer, primary peritoneal carcinoma, or fallopian tube cancerRebecca Kristeleit, Irina Davidenko, Vadim Shirinkin, et al.Bioorganic & Medicinal Chemistry Letters|November 23, 2007
Discovery of beta-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitorsJames J-W Duan, Lihua Chen, Zhonghui Lu, et al.Journal of Medicinal Chemistry|November 1, 2002
Discovery of gamma-lactam hydroxamic acids as selective inhibitors of tumor necrosis factor alpha converting enzyme: design, synthesis, and structure-activity relationshipsJames J-W Duan, Lihua Chen, Zelda R Wasserman, et al.Bioorganic & Medicinal Chemistry Letters|June 5, 2003
Discovery of N-hydroxy-2-(2-oxo-3-pyrrolidinyl)acetamides as potent and selective inhibitors of tumor necrosis factor-alpha converting enzyme (TACE)James J-W Duan, Zhonghui Lu, Chu-Biao Xue, et al.Bioorganic & Medicinal Chemistry Letters|March 7, 2006
Synthesis and structure-activity relationship of a novel, achiral series of TNF-alpha converting enzyme inhibitorsJohn L Gilmore, Bryan W King, Cathy Harris, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|March 17, 2007
Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancerJordan S Fridman, Eian Caulder, Michael Hansbury, et al.Bioorganic & Medicinal Chemistry Letters|August 26, 2006
2,4-Disubstituted piperidines as selective CC chemokine receptor 3 (CCR3) antagonists: synthesis and selectivityPaul S Watson, Bin Jiang, Kim Harrison, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|September 16, 2011
A novel kinase inhibitor, INCB28060, blocks c-MET-dependent signaling, neoplastic activities, and cross-talk with EGFR and HER-3Xiangdong Liu, Qian Wang, Gengjie Yang, et al.Pageof 5