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Bioorganic & Medicinal Chemistry Letters|September 11, 2004
Synthesis and structure-activity relationship of a novel sulfone series of TNF-alpha converting enzyme inhibitorsChu-Biao Xue, Xiao-Tao Chen, Xiaohua He, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 28, 2007
Pharmacokinetics and pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a potent and selective inhibitor of tumor necrosis factor alpha-converting enzyme in rodents, dogs, chimpanzees, and humansMingxin Qian, Stephen A Bai, Bernice Brogdon, et al.
Bioorganic & Medicinal Chemistry Letters|December 3, 2003
Rational design, synthesis and structure-activity relationships of a cyclic succinate series of TNF-alpha converting enzyme inhibitors. Part 2: lead optimizationChu-Biao Xue, Xiaohua He, John Roderick, et al.
The Journal of Pharmacology and Experimental Therapeutics|April 15, 2006
Selective inhibition of eosinophil influx into the lung by small molecule CC chemokine receptor 3 antagonists in mouse models of allergic inflammationAnuk M Das, Krishna G Vaddi, Kimberly A Solomon, et al.
Bioorganic & Medicinal Chemistry Letters|February 6, 2007
A new 4-(2-methylquinolin-4-ylmethyl)phenyl P1' group for the beta-amino hydroxamic acid derived TACE inhibitorsXiao-Tao Chen, Bahman Ghavimi, Ronald L Corbett, et al.
Bioorganic & Medicinal Chemistry Letters|March 27, 2003
Potent and selective aggrecanase inhibitors containing cyclic P1 substituentsRobert J Cherney, Ruowei Mo, Dayton T Meyer, et al.
The Journal of Investigative Dermatology|June 17, 2011
Preclinical evaluation of local JAK1 and JAK2 inhibition in cutaneous inflammationJordan S Fridman, Peggy A Scherle, Robert Collins, et al.
Bioorganic & Medicinal Chemistry Letters|March 18, 2004
Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonistsJeffrey G Varnes, Daniel S Gardner, Joseph B Santella, et al.
Journal of Medicinal Chemistry|May 2, 2003
Design, synthesis, and evaluation of benzothiadiazepine hydroxamates as selective tumor necrosis factor-alpha converting enzyme inhibitorsRobert J Cherney, James J-W Duan, Matthew E Voss, et al.
Cancer Cell|July 18, 2006
Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancerBin-Bing S Zhou, Michael Peyton, Biao He, et al.
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