Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Robert J Riley

Showing results (11-20 of 42) with videos related to

Pageof 5
Sort By:
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 14, 2008
Functional consequences of active hepatic uptake on cytochrome P450 inhibition in rat and human hepatocytesKen Grime, Peter J H Webborn, Robert J Riley
Expert Opinion on Drug Metabolism & Toxicology|October 7, 2022
Studying the right transporter at the right time: an <i>in vitro</i> strategy for assessing drug-drug interaction risk during drug discovery and developmentRobert Elsby, Hayley Atkinson, Philip Butler, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 9, 2018
Development and Characterization of a Human Hepatocyte Low Intrinsic Clearance Assay for Use in Drug DiscoveryPaul Lancett, Beth Williamson, Patrick Barton, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 4, 2005
A unified model for predicting human hepatic, metabolic clearance from in vitro intrinsic clearance data in hepatocytes and microsomesRobert J Riley, D F McGinnity, R P Austin
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 6, 2005
Prediction of CYP2C9-mediated drug-drug interactions: a comparison using data from recombinant enzymes and human hepatocytesDermot F McGinnity, James Tucker, Steve Trigg, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 24, 2004
The binding of drugs to hepatocytes and its relationship to physicochemical propertiesRupert P Austin, Patrick Barton, Sarfraz Mohmed, et al.
Molecular Pharmaceutics|May 1, 2009
Impact of hepatic uptake transporters on pharmacokinetics and drug-drug interactions: use of assays and models for decision making in the pharmaceutical industryMathew G Soars, Peter J H Webborn, Robert J Riley
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|November 18, 2008
Mechanism-based inhibition of cytochrome P450 enzymes: an evaluation of early decision making in vitro approaches and drug-drug interaction prediction methodsKenneth H Grime, James Bird, Douglas Ferguson, et al.
Expert Opinion on Drug Discovery|September 21, 2019
Estimating human ADME properties, pharmacokinetic parameters and likely clinical dose in drug discoveryAdam J Lucas, Joanne L Sproston, Patrick Barton, et al.
Chemico-Biological Interactions|January 9, 2007
The pivotal role of hepatocytes in drug discoveryMatthew G Soars, Dermot F McGinnity, Ken Grime, et al.
Pageof 5

Showing results (11-20 of 42) with videos related to

Sort By:
Pageof 5
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 14, 2008
Functional consequences of active hepatic uptake on cytochrome P450 inhibition in rat and human hepatocytesKen Grime, Peter J H Webborn, Robert J Riley
Expert Opinion on Drug Metabolism & Toxicology|October 7, 2022
Studying the right transporter at the right time: an <i>in vitro</i> strategy for assessing drug-drug interaction risk during drug discovery and developmentRobert Elsby, Hayley Atkinson, Philip Butler, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 9, 2018
Development and Characterization of a Human Hepatocyte Low Intrinsic Clearance Assay for Use in Drug DiscoveryPaul Lancett, Beth Williamson, Patrick Barton, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 4, 2005
A unified model for predicting human hepatic, metabolic clearance from in vitro intrinsic clearance data in hepatocytes and microsomesRobert J Riley, D F McGinnity, R P Austin
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 6, 2005
Prediction of CYP2C9-mediated drug-drug interactions: a comparison using data from recombinant enzymes and human hepatocytesDermot F McGinnity, James Tucker, Steve Trigg, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 24, 2004
The binding of drugs to hepatocytes and its relationship to physicochemical propertiesRupert P Austin, Patrick Barton, Sarfraz Mohmed, et al.
Molecular Pharmaceutics|May 1, 2009
Impact of hepatic uptake transporters on pharmacokinetics and drug-drug interactions: use of assays and models for decision making in the pharmaceutical industryMathew G Soars, Peter J H Webborn, Robert J Riley
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|November 18, 2008
Mechanism-based inhibition of cytochrome P450 enzymes: an evaluation of early decision making in vitro approaches and drug-drug interaction prediction methodsKenneth H Grime, James Bird, Douglas Ferguson, et al.
Expert Opinion on Drug Discovery|September 21, 2019
Estimating human ADME properties, pharmacokinetic parameters and likely clinical dose in drug discoveryAdam J Lucas, Joanne L Sproston, Patrick Barton, et al.
Chemico-Biological Interactions|January 9, 2007
The pivotal role of hepatocytes in drug discoveryMatthew G Soars, Dermot F McGinnity, Ken Grime, et al.
Pageof 5