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Journal of Medicinal Chemistry|January 28, 2016
Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical TrialsBrian K Albrecht, Victor S Gehling, Michael C Hewitt, et al.
Journal of Medicinal Chemistry|August 5, 2022
GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1Alexander M Taylor, Chris Bailey, Lisa D Belmont, et al.
ACS Medicinal Chemistry Letters|July 26, 2017
GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2)Terry D Crawford, James E Audia, Steve Bellon, et al.
The Journal of Biological Chemistry|April 9, 2016
Regulatory T Cell Modulation by CBP/EP300 Bromodomain InhibitionSrimoyee Ghosh, Alexander Taylor, Melissa Chin, et al.
ACS Medicinal Chemistry Letters|May 19, 2016
Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)Alexander M Taylor, Alexandre Côté, Michael C Hewitt, et al.
Nature Communications|July 11, 2023
Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disordersCarolina Gracia-Diaz, Yijing Zhou, Qian Yang, et al.
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