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Journal of Medicinal Chemistry|December 14, 2011
Synthesis and biological profile of the pan-vascular endothelial growth factor receptor/tyrosine kinase with immunoglobulin and epidermal growth factor-like homology domains 2 (VEGF-R/TIE-2) inhibitor 11-(2-methylpropyl)-12,13-dihydro-2-methyl-8-(pyrimidin-2-ylamino)-4H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one (CEP-11981): a novel oncology therapeutic agentRobert L Hudkins, Nadine C Becknell, Allison L Zulli, et al.Blood|October 29, 2005
Anaplastic lymphoma kinase activity is essential for the proliferation and survival of anaplastic large-cell lymphoma cellsWeihua Wan, Mark S Albom, Lihui Lu, et al.Bioorganic & Medicinal Chemistry Letters|July 26, 2011
Identification of pyridazin-3-one derivatives as potent, selective histamine H₃ receptor inverse agonists with robust wake activityRobert L Hudkins, Lisa D Aimone, Thomas R Bailey, et al.Journal of Medicinal Chemistry|August 22, 2008
Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine modelsRobert L Hudkins, James L Diebold, Ming Tao, et al.Pageof 5