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The Journal of Biological Chemistry|May 8, 2009
FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific mannerAvvaru N Suhasini, Joshua A Sommers, Aaron C Mason, et al.
The Journal of Biological Chemistry|June 2, 2026
SARS-CoV-2 Nsp13 Helicase Resolves G-Quadruplexes and is Inhibited by G4 Ligands or an Anti-Viral Regulator: Implications for G4 Anti-Coronavirus TherapiesJoe C George, Tomasz Kulikowicz, Pierce T Bombard, et al.
Molecular Biology of the Cell|December 6, 2003
WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication forkSudha Sharma, Marit Otterlei, Joshua A Sommers, et al.
Molecular and Cellular Biology|March 27, 2013
Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage responseAvvaru N Suhasini, Joshua A Sommers, Parameswary A Muniandy, et al.
Plos Genetics|July 14, 2012
FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage responseJenny Xie, Min Peng, Shawna Guillemette, et al.
Nucleic Acids Research|October 29, 2013
Detection of G-quadruplex DNA in mammalian cellsAlexander Henderson, Yuliang Wu, Yu Chuan Huang, et al.
Blood|July 20, 2010
Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexesYuliang Wu, Joshua A Sommers, Avvaru N Suhasini, et al.
The Journal of Biological Chemistry|August 13, 2013
Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stabilitySanjay Kumar Bharti, Joshua A Sommers, Fourbears George, et al.
The Journal of Biological Chemistry|May 27, 2016
Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: SUBSTRATE SPECIFICITY, DNA BRANCH MIGRATION, AND ABILITY TO OVERCOME BLOCKADES TO DNA UNWINDINGIrfan Khan, Jack D Crouch, Sanjay Kumar Bharti, et al.
Plos One|January 10, 2019
A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN)Joshua A Sommers, Tomasz Kulikowicz, Deborah L Croteau, et al.
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