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Bioorganic & Medicinal Chemistry Letters|April 25, 2008
Discovery of a novel and potent series of thieno[3,2-b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinasesStephen Claridge, Franck Raeppel, Marie-Claude Granger, et al.Bioorganic & Medicinal Chemistry Letters|November 6, 2007
N-(2-Amino-phenyl)-4-(heteroarylmethyl)-benzamides as new histone deacetylase inhibitorsArkadii Vaisburg, Isabelle Paquin, Naomy Bernstein, et al.Bioorganic & Medicinal Chemistry Letters|December 28, 2007
Design and synthesis of 4-[(s-triazin-2-ylamino)methyl]-N-(2-aminophenyl)-benzamides and their analogues as a novel class of histone deacetylase inhibitorsIsabelle Paquin, Stéphane Raeppel, Silvana Leit, et al.Science Translational Medicine|November 20, 2015
AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancerDavid Hong, Razelle Kurzrock, Youngsoo Kim, et al.Journal for Immunotherapy of Cancer|April 7, 2022
Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancerAlexey Revenko, Larissa S Carnevalli, Charles Sinclair, et al.Journal for Immunotherapy of Cancer|November 18, 2018
STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trialMatthew J Reilley, Patricia McCoon, Carl Cook, et al.Blood|June 2, 2021
Specific targeting of the KRAS mutational landscape in myeloma as a tool to unveil the elicited antitumor activityAntonio Sacco, Cinzia Federico, Katia Todoerti, et al.The Journal of Clinical Investigation|September 26, 2018
Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cellsAditi Shastri, Gaurav Choudhary, Margarida Teixeira, et al.Nature Communications|June 1, 2022
The androgen receptor is a therapeutic target in desmoplastic small round cell sarcomaSalah-Eddine Lamhamedi-Cherradi, Mayinuer Maitituoheti, Brian A Menegaz, et al.Pageof 9