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Plos One|February 2, 2022
Oral nimodipine treatment has no effect on amyloid pathology or neuritic dystrophy in the 5XFAD mouse model of amyloidosisKatherine R Sadleir, Jelena Popovic, Ammaarah Khatri, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|October 16, 2009
The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potentialRobert Vassar, Dora M Kovacs, Riqiang Yan, et al.
Molecular Neurodegeneration|January 9, 2015
Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP levelKatherine R Sadleir, William A Eimer, Sarah L Cole, et al.
Molecular Neurodegeneration|August 25, 2010
BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localizationBrian D Hitt, Thomas C Jaramillo, Dane M Chetkovich, et al.
Molecular Neurodegeneration|December 30, 2011
The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulbTharinda W Rajapaksha, William A Eimer, Thomas C Bozza, et al.
Current Alzheimer Research|August 8, 2013
Elevated Aβ42 in aged, non-demented individuals with cerebral atherosclerosisKatherine R Sadleir, David A Bennett, Julie A Schneider, et al.
Plos One|September 15, 2025
ACE1 does not influence cerebral Aβ degradation or amyloid plaque accumulation in 5XFAD miceSohee Jeon, Alia O Alia, Jelena Popovic, et al.
Plos One|July 4, 2014
Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's diseaseKatherine R Sadleir, William A Eimer, Randal J Kaufman, et al.
Current Alzheimer Research|May 17, 2022
Poloxamer-188 Exacerbates Brain Amyloidosis, Presynaptic Dystrophies, and Pathogenic Microglial Activation in 5XFAD MiceAntonio Di Meco, Shahrnaz Kemal, Jelena Popovic, et al.
Molecular Neurodegeneration|June 3, 2014
Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer's diseaseLokesh Kukreja, Gregory C Kujoth, Tomas A Prolla, et al.
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