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Methods in Molecular Biology (Clifton, N.J.)|July 1, 2005
Crystallization of cyclic nucleotide phosphodiesterasesHengming Ke, Qing Huai, Robert X XuJournal of Molecular Biology|March 9, 2004
Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipramRobert X Xu, Warren J Rocque, Millard H Lambert, et al.Bioorganic & Medicinal Chemistry Letters|August 30, 2008
Discovery of a novel class of PPARdelta partial agonistsBarry G Shearer, Hari S Patel, Andrew N Billin, et al.Molecular Cell|December 22, 2004
A structural basis for constitutive activity in the human CAR/RXRalpha heterodimerRobert X Xu, Millard H Lambert, Bruce B Wisely, et al.Journal of Medicinal Chemistry|February 5, 2010
Identification and characterization of 4-chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonistBarry G Shearer, Robert W Wiethe, Adam Ashe, et al.Bioorganic & Medicinal Chemistry Letters|February 7, 2006
Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: the discovery of GW0385John F Miller, C Webster Andrews, Michael Brieger, et al.Bioorganic & Medicinal Chemistry Letters|March 19, 2011
Phenoxyacetic acids as PPARδ partial agonists: synthesis, optimization, and in vivo efficacyKaren A Evans, Barry G Shearer, David D Wisnoski, et al.Bioorganic & Medicinal Chemistry Letters|July 30, 2011
Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonistMairi Sime, Amanda C Allan, Paul Chapman, et al.Cell|February 15, 2005
Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1Irina N Krylova, Elena P Sablin, Jamie Moore, et al.Journal of Medicinal Chemistry|January 25, 2007
Substituted 2-[(4-aminomethyl)phenoxy]-2-methylpropionic acid PPARalpha agonists. 1. Discovery of a novel series of potent HDLc raising agentsMichael L Sierra, Véronique Beneton, Anne-Bénédict Boullay, et al.Pageof 1