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Journal of Molecular Biology|April 14, 2009
Dopamine and the dopamine oxidation product 5,6-dihydroxylindole promote distinct on-pathway and off-pathway aggregation of alpha-synuclein in a pH-dependent mannerChi L L Pham, Su Ling Leong, Feda E Ali, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|November 14, 2008
Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicityLin Wai Hung, Giuseppe D Ciccotosto, Eleni Giannakis, et al.Plos One|February 14, 2015
The N-terminal residues 43 to 60 form the interface for dopamine mediated α-synuclein dimerisationSu Ling Leong, Mark G Hinds, Andrea R Connor, et al.Metallomics : Integrated Biometal Science|November 23, 2018
Characterization of the metal status of natively purified alpha-synuclein from human blood, brain tissue, or recombinant sources using size exclusion ICP-MS reveals no significant binding of Cu, Fe or ZnAmber Lothian, Larissa Lago, Soumya Mukherjee, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|January 29, 2010
Alleviating transcriptional inhibition of the norepinephrine slc6a2 transporter gene in depolarized neuronsK N Harikrishnan, Richard Bayles, Giuseppe D Ciccotosto, et al.Acta Crystallographica. Section F, Structural Biology and Crystallization Communications|March 2, 2006
Crystallization and preliminary crystallographic studies of the copper-binding domain of the amyloid precursor protein of Alzheimer's diseaseGeoffrey K-W Kong, Denise Galatis, Kevin J Barnham, et al.Biophysical Journal|December 11, 2007
Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptideDeborah J Tew, Stephen P Bottomley, David P Smith, et al.Journal of Alzheimer'S Disease : JAD|January 12, 2010
Histidine 14 modulates membrane binding and neurotoxicity of the Alzheimer's disease amyloid-beta peptideDanielle G Smith, Giuseppe D Ciccotosto, Deborah J Tew, et al.Plos One|March 18, 2011
Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's diseasePaul A Adlard, Laura Bica, Anthony R White, et al.Metallomics : Integrated Biometal Science|August 8, 2014
Quantitation and localization of intracellular redox active metals by X-ray fluorescence microscopy in cortical neurons derived from APP and APLP2 knockout tissueGiuseppe D Ciccotosto, Simon A James, Matteo Altissimo, et al.Pageof 16