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Gastroenterology|June 3, 2020
Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial RegenerationGiovanni Sorrentino, Alessia Perino, Ece Yildiz, et al.Advances in Experimental Medicine and Biology|June 23, 2004
Modulation of the kynurine pathway of tryptophan metabolism in search for neuroprotective agents. Focus on kynurenine-3-hydroxylaseRoberto Pellicciari, Laura Amori, Gabriele Costantino, et al.The Journal of Pharmacology and Experimental Therapeutics|June 28, 2005
Cross-talk between farnesoid-X-receptor (FXR) and peroxisome proliferator-activated receptor gamma contributes to the antifibrotic activity of FXR ligands in rodent models of liver cirrhosisStefano Fiorucci, Giovanni Rizzo, Elisabetta Antonelli, et al.Bioorganic & Medicinal Chemistry|May 21, 2013
Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: role of the chirality on the biological activityMaura Marinozzi, Andrea Carotti, Roccaldo Sardella, et al.The Journal of Biological Chemistry|June 3, 2010
Novel polymorphisms of nuclear receptor SHP associated with functional and structural changesTaofeng Zhou, Yuxia Zhang, Antonio Macchiarulo, et al.Journal of Medicinal Chemistry|August 30, 2007
Synthesis, molecular modeling studies, and preliminary pharmacological characterization of all possible 2-(2'-sulfonocyclopropyl)glycine stereoisomers as conformationally constrained L-homocysteic acid analogsRoberto Pellicciari, Maura Marinozzi, Antonio Macchiarulo, et al.Molecular Cell|April 30, 2003
Structural basis for bile acid binding and activation of the nuclear receptor FXRLi-Zhi Mi, Srikripa Devarakonda, Joel M Harp, et al.Medchemcomm|November 2, 2019
Dissecting the allosteric FXR modulation: a chemical biology approach using guggulsterone as a chemical toolDaniela Passeri, Andrea Carotti, Jose M Ramos Pittol, et al.Journal of Medicinal Chemistry|August 10, 2007
Nongenomic actions of bile acids. Synthesis and preliminary characterization of 23- and 6,23-alkyl-substituted bile acid derivatives as selective modulators for the G-protein coupled receptor TGR5Roberto Pellicciari, Hiroyuki Sato, Antimo Gioiello, et al.ACS Medicinal Chemistry Letters|April 19, 2019
Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR AgonistsBruno Cerra, Andrea Carotti, Daniela Passeri, et al.Pageof 15