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Nature Reviews. Drug Discovery
|
August 13, 2016
Biophysics in drug discovery: impact, challenges and opportunities
Jean-Paul Renaud, Chun-Wa Chung, U Helena Danielson, et al.
Chemical Science
|
November 23, 2017
Increase of enzyme activity through specific covalent modification with fragments
John F Darby, Masakazu Atobe, James D Firth, et al.
Cells
|
September 28, 2021
P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells
Elizabeth Hampson, Elpida Tsonou, Martin J Baker, et al.
The Journal of Biological Chemistry
|
September 7, 2015
Tripartite ATP-independent Periplasmic (TRAP) Transporters Use an Arginine-mediated Selectivity Filter for High Affinity Substrate Binding
Marcus Fischer, Adam P Hopkins, Emmanuele Severi, et al.
The Biochemical Journal
|
October 28, 2020
Fragment-derived modulators of an industrial β-glucosidase
Eleni Makraki, John F Darby, Marta G Carneiro, et al.
Bioorganic & Medicinal Chemistry
|
May 5, 2015
Lead-oriented synthesis: Investigation of organolithium-mediated routes to 3-D scaffolds and 3-D shape analysis of a virtual lead-like library
Monique Lüthy, Mary C Wheldon, Chehasnah Haji-Cheteh, et al.
Analytical Chemistry
|
June 29, 2013
Fragment screening by weak affinity chromatography: comparison with established techniques for screening against HSP90
Elinor Meiby, Heather Simmonite, Loic le Strat, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
February 22, 2002
Structure of a Cys25-->Ser mutant of human cathepsin S
Johan P Turkenburg, Marieke B A C Lamers, A Marek Brzozowski, et al.
Journal of Chemical Information and Modeling
|
May 25, 2023
Fragment Merging Using a Graph Database Samples Different Catalogue Space than Similarity Search
Stephanie Wills, Ruben Sanchez-Garcia, Tim Dudgeon, et al.
Journal of Chemical Information and Computer Sciences
|
November 24, 2004
Design and characterization of libraries of molecular fragments for use in NMR screening against protein targets
Nicolas Baurin, Fareed Aboul-Ela, Xavier Barril, et al.
Page
of 8
Search research articles
Search
Showing results (31-40 of 74) with videos related to
Sort By:
Page
of 8
Nature Reviews. Drug Discovery
|
August 13, 2016
Biophysics in drug discovery: impact, challenges and opportunities
Jean-Paul Renaud, Chun-Wa Chung, U Helena Danielson, et al.
Chemical Science
|
November 23, 2017
Increase of enzyme activity through specific covalent modification with fragments
John F Darby, Masakazu Atobe, James D Firth, et al.
Cells
|
September 28, 2021
P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells
Elizabeth Hampson, Elpida Tsonou, Martin J Baker, et al.
The Journal of Biological Chemistry
|
September 7, 2015
Tripartite ATP-independent Periplasmic (TRAP) Transporters Use an Arginine-mediated Selectivity Filter for High Affinity Substrate Binding
Marcus Fischer, Adam P Hopkins, Emmanuele Severi, et al.
The Biochemical Journal
|
October 28, 2020
Fragment-derived modulators of an industrial β-glucosidase
Eleni Makraki, John F Darby, Marta G Carneiro, et al.
Bioorganic & Medicinal Chemistry
|
May 5, 2015
Lead-oriented synthesis: Investigation of organolithium-mediated routes to 3-D scaffolds and 3-D shape analysis of a virtual lead-like library
Monique Lüthy, Mary C Wheldon, Chehasnah Haji-Cheteh, et al.
Analytical Chemistry
|
June 29, 2013
Fragment screening by weak affinity chromatography: comparison with established techniques for screening against HSP90
Elinor Meiby, Heather Simmonite, Loic le Strat, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
February 22, 2002
Structure of a Cys25-->Ser mutant of human cathepsin S
Johan P Turkenburg, Marieke B A C Lamers, A Marek Brzozowski, et al.
Journal of Chemical Information and Modeling
|
May 25, 2023
Fragment Merging Using a Graph Database Samples Different Catalogue Space than Similarity Search
Stephanie Wills, Ruben Sanchez-Garcia, Tim Dudgeon, et al.
Journal of Chemical Information and Computer Sciences
|
November 24, 2004
Design and characterization of libraries of molecular fragments for use in NMR screening against protein targets
Nicolas Baurin, Fareed Aboul-Ela, Xavier Barril, et al.
Page
of 8