Search research articles
Contact Us
Filters
Showing results (61-70 of 74) with videos related to
Page
of 8
Sort By:
Chemical Science
|
October 3, 2025
Design, modular synthesis and screening of 58 shape-diverse 3-D fragments
Thomas D Downes, S Paul Jones, James D Firth, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)
|
April 22, 2020
Design and Synthesis of 56 Shape-Diverse 3D Fragments
Thomas D Downes, S Paul Jones, Hanna F Klein, et al.
RSC Medicinal Chemistry
|
December 18, 2023
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase
Naoki Kuki, David L Walmsley, Kazuo Kanai, et al.
Journal of Medicinal Chemistry
|
July 25, 2019
Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity
Zoltan Szlávik, Levente Ondi, Márton Csékei, et al.
ACS Omega
|
August 29, 2019
Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1
James B Murray, James Davidson, Ijen Chen, et al.
Journal of Medicinal Chemistry
|
November 4, 2020
Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor
Zoltan Szlavik, Marton Csekei, Attila Paczal, et al.
Journal of Medicinal Chemistry
|
October 13, 2017
Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)
Douglas S Williamson, Garrick P Smith, Pamela Acheson-Dossang, et al.
Journal of Medicinal Chemistry
|
November 19, 2020
Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity
Yousuke Yamada, Hajime Takashima, David Lee Walmsley, et al.
Journal of Medicinal Chemistry
|
June 12, 2026
Structure-Based Discovery of Potent BCL-XL Inhibitors through Rescaffolding
Matyas Pal Timari, Attila Paczal, Andras Herner, et al.
Molecular Cancer Therapeutics
|
April 14, 2007
Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues
Swee Y Sharp, Chrisostomos Prodromou, Kathy Boxall, et al.
Page
of 8
Search research articles
Search
Showing results (61-70 of 74) with videos related to
Sort By:
Page
of 8
Chemical Science
|
October 3, 2025
Design, modular synthesis and screening of 58 shape-diverse 3-D fragments
Thomas D Downes, S Paul Jones, James D Firth, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)
|
April 22, 2020
Design and Synthesis of 56 Shape-Diverse 3D Fragments
Thomas D Downes, S Paul Jones, Hanna F Klein, et al.
RSC Medicinal Chemistry
|
December 18, 2023
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase
Naoki Kuki, David L Walmsley, Kazuo Kanai, et al.
Journal of Medicinal Chemistry
|
July 25, 2019
Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity
Zoltan Szlávik, Levente Ondi, Márton Csékei, et al.
ACS Omega
|
August 29, 2019
Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1
James B Murray, James Davidson, Ijen Chen, et al.
Journal of Medicinal Chemistry
|
November 4, 2020
Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor
Zoltan Szlavik, Marton Csekei, Attila Paczal, et al.
Journal of Medicinal Chemistry
|
October 13, 2017
Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)
Douglas S Williamson, Garrick P Smith, Pamela Acheson-Dossang, et al.
Journal of Medicinal Chemistry
|
November 19, 2020
Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity
Yousuke Yamada, Hajime Takashima, David Lee Walmsley, et al.
Journal of Medicinal Chemistry
|
June 12, 2026
Structure-Based Discovery of Potent BCL-XL Inhibitors through Rescaffolding
Matyas Pal Timari, Attila Paczal, Andras Herner, et al.
Molecular Cancer Therapeutics
|
April 14, 2007
Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues
Swee Y Sharp, Chrisostomos Prodromou, Kathy Boxall, et al.
Page
of 8