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Roger J Butlin

Showing results (1-10 of 10) with videos related to

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Angewandte Chemie (International Ed. in English)|May 18, 2012
A mild benzannulation through directed cycloaddition reactionsJames D Kirkham, Roger J Butlin, Joseph P A Harrity
Organic & Biomolecular Chemistry|April 4, 2008
Synthesis of carboxylic amides by ring-opening of oxazolidinones with Grignard reagentsDavid Bensa, Iain Coldham, Pia Feinäugle, et al.
Chemical Communications (Cambridge, England)|August 9, 2011
Stereoselective approaches to 2,3,6-trisubstituted piperidines. An enantiospecific synthesis of quinolizidine (-)-217ANicole C Mancey, Nicolas Sandon, Anne-Laure Auvinet, et al.
Bioorganic & Medicinal Chemistry Letters|August 20, 2011
Strategies to improve in vivo toxicology outcomes for basic candidate drug moleculesTim Luker, Lilian Alcaraz, Kamaldeep K Chohan, et al.
Bioorganic & Medicinal Chemistry Letters|November 9, 2011
Discovery, optimisation and in vivo evaluation of novel GPR119 agonistsKaty J Brocklehurst, Anders Broo, Roger J Butlin, et al.
Journal of Medicinal Chemistry|May 2, 2012
Use of small-molecule crystal structures to address solubility in a novel series of G protein coupled receptor 119 agonists: optimization of a lead and in vivo evaluationJames S Scott, Alan M Birch, Katy J Brocklehurst, et al.
Journal of Medicinal Chemistry|April 5, 2017
Indazole-6-phenylcyclopropylcarboxylic Acids as Selective GPR120 Agonists with in Vivo EfficacyWilliam McCoull, Andrew Bailey, Peter Barton, et al.
Journal of Medicinal Chemistry|November 3, 2012
Design and optimization of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1 (DGAT1) leading to a clinical candidate dimethylpyrazinecarboxamide phenylcyclohexylacetic acid (AZD7687)Jonas G Barlind, Udo A Bauer, Alan M Birch, et al.
Bioorganic & Medicinal Chemistry Letters|May 22, 2012
Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetesWilliam McCoull, Matthew S Addie, Alan M Birch, et al.
Nature Cancer|November 18, 2021
Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemiaMelissa B Pappalardi, Kathryn Keenan, Mark Cockerill, et al.
Pageof 1

Showing results (1-10 of 10) with videos related to

Sort By:
Pageof 1
Angewandte Chemie (International Ed. in English)|May 18, 2012
A mild benzannulation through directed cycloaddition reactionsJames D Kirkham, Roger J Butlin, Joseph P A Harrity
Organic & Biomolecular Chemistry|April 4, 2008
Synthesis of carboxylic amides by ring-opening of oxazolidinones with Grignard reagentsDavid Bensa, Iain Coldham, Pia Feinäugle, et al.
Chemical Communications (Cambridge, England)|August 9, 2011
Stereoselective approaches to 2,3,6-trisubstituted piperidines. An enantiospecific synthesis of quinolizidine (-)-217ANicole C Mancey, Nicolas Sandon, Anne-Laure Auvinet, et al.
Bioorganic & Medicinal Chemistry Letters|August 20, 2011
Strategies to improve in vivo toxicology outcomes for basic candidate drug moleculesTim Luker, Lilian Alcaraz, Kamaldeep K Chohan, et al.
Bioorganic & Medicinal Chemistry Letters|November 9, 2011
Discovery, optimisation and in vivo evaluation of novel GPR119 agonistsKaty J Brocklehurst, Anders Broo, Roger J Butlin, et al.
Journal of Medicinal Chemistry|May 2, 2012
Use of small-molecule crystal structures to address solubility in a novel series of G protein coupled receptor 119 agonists: optimization of a lead and in vivo evaluationJames S Scott, Alan M Birch, Katy J Brocklehurst, et al.
Journal of Medicinal Chemistry|April 5, 2017
Indazole-6-phenylcyclopropylcarboxylic Acids as Selective GPR120 Agonists with in Vivo EfficacyWilliam McCoull, Andrew Bailey, Peter Barton, et al.
Journal of Medicinal Chemistry|November 3, 2012
Design and optimization of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1 (DGAT1) leading to a clinical candidate dimethylpyrazinecarboxamide phenylcyclohexylacetic acid (AZD7687)Jonas G Barlind, Udo A Bauer, Alan M Birch, et al.
Bioorganic & Medicinal Chemistry Letters|May 22, 2012
Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetesWilliam McCoull, Matthew S Addie, Alan M Birch, et al.
Nature Cancer|November 18, 2021
Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemiaMelissa B Pappalardi, Kathryn Keenan, Mark Cockerill, et al.
Pageof 1