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Pharmacological Reports : PR|October 27, 2019
The α7 nicotinic acetylcholine receptor positive allosteric modulator prevents lipopolysaccharide-induced allodynia, hyperalgesia and TNF-α in the hippocampus in miceMuzaffar Abbas, Sami Alzarea, Roger L Papke, et al.
CNS & Neurological Disorders Drug Targets|December 31, 2020
Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a Mouse Model of Inflammatory PainMuzaffar Abbas, Sami Alzarea, Roger L Papke, et al.
Molecular Pharmacology|September 9, 2010
Tethered agonist analogs as site-specific probes for domains of the human α7 nicotinic acetylcholine receptor that differentially regulate activation and desensitizationJingyi Wang, Nicole A Horenstein, Clare Stokes, et al.
The Journal of Biological Chemistry|May 5, 2012
Potential state-selective hydrogen bond formation can modulate activation and desensitization of the α7 nicotinic acetylcholine receptorJingyi Wang, Roger L Papke, Clare Stokes, et al.
European Journal of Pharmacology|October 29, 2013
Similar activity of mecamylamine stereoisomers in vitro and in vivoRoger L Papke, Clare Stokes, Pretal Muldoon, et al.
Neuropharmacology|June 30, 2022
Coffee and cigarettes: Modulation of high and low sensitivity α4β2 nicotinic acetylcholine receptors by n-MP, a biomarker of coffee consumptionRoger L Papke, Madison Karaffa, Nicole A Horenstein, et al.
Molecular Pharmacology|September 28, 2005
An alpha7 nicotinic acetylcholine receptor gain-of-function mutant that retains pharmacological fidelityAndon N Placzek, Francesca Grassi, Edwin M Meyer, et al.
The Journal of General Physiology|March 30, 2011
The effective opening of nicotinic acetylcholine receptors with single agonist binding sitesDustin K Williams, Clare Stokes, Nicole A Horenstein, et al.
Molecular Pharmacology|July 26, 2012
Intrinsically low open probability of α7 nicotinic acetylcholine receptors can be overcome by positive allosteric modulation and serum factors leading to the generation of excitotoxic currents at physiological temperaturesDustin K Williams, Can Peng, Matthew R Kimbrell, et al.
The Journal of Pharmacology and Experimental Therapeutics|April 3, 2009
Differential regulation of receptor activation and agonist selectivity by highly conserved tryptophans in the nicotinic acetylcholine receptor binding siteDustin K Williams, Clare Stokes, Nicole A Horenstein, et al.
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