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Journal of Medicinal Chemistry|July 18, 2009
3,5-Diphenylpent-2-enoic acids as allosteric activators of the protein kinase PDK1: structure-activity relationships and thermodynamic characterization of binding as paradigms for PIF-binding pocket-targeting compoundsAdriana Stroba, Francis Schaeffer, Valerie Hindie, et al.European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|August 13, 2016
Pharmacological inhibition of protein kinase C (PKC)ζ downregulates the expression of cytokines involved in the pathogenesis of chronic obstructive pulmonary disease (COPD)Mohammad Abdel-Halim, Sarah S Darwish, Ahmed K ElHady, et al.Journal of Chemical Information and Modeling|October 10, 2022
Modeling the Effect of Hydrophobicity on the Passive Permeation of Solutes across a Bacterial Model MembraneCarla F Sousa, Mohamed A M Kamal, Robert Richter, et al.Chemmedchem|July 13, 2013
6-Aryl and heterocycle quinazoline derivatives as potent EGFR inhibitors with improved activity toward gefitinib-sensitive and -resistant tumor cell linesMostafa M Hamed, Dalal A Abou El Ella, Adam B Keeton, et al.Journal of Controlled Release : Official Journal of the Controlled Release Society|July 6, 2014
Antibiotic-free nanotherapeutics: ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitorsNoha Nafee, Ayman Husari, Christine K Maurer, et al.The Journal of Steroid Biochemistry and Molecular Biology|April 10, 2019
Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthaseMuhammad Akram, Melanie Patt, Teresa Kaserer, et al.Journal of Medicinal Chemistry|November 14, 2012
Structural optimization of 2,5-thiophene amides as highly potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors for the treatment of osteoporosisSandrine Marchais-Oberwinkler, Kuiying Xu, Marie Wetzel, et al.Journal of Medicinal Chemistry|August 5, 2008
Overcoming undesirable CYP1A2 inhibition of pyridylnaphthalene-type aldosterone synthase inhibitors: influence of heteroaryl derivatization on potency and selectivityRalf Heim, Simon Lucas, Cornelia M Grombein, et al.Journal of Medicinal Chemistry|August 8, 2013
Discovery and biophysical characterization of 2-amino-oxadiazoles as novel antagonists of PqsR, an important regulator of Pseudomonas aeruginosa virulenceMichael Zender, Tobias Klein, Claudia Henn, et al.Journal of Medicinal Chemistry|May 30, 2003
Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapyOmoshile O Clement, Clive M Freeman, Rolf W Hartmann, et al.Pageof 26