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Journal of Medicinal Chemistry|March 8, 2008
Design, synthesis, and biological evaluation of (hydroxyphenyl)naphthalene and -quinoline derivatives: potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseasesMartin Frotscher, Erika Ziegler, Sandrine Marchais-Oberwinkler, et al.Journal of Medicinal Chemistry|June 2, 2017
Lead Optimization Generates CYP11B1 Inhibitors of Pyridylmethyl Isoxazole Type with Improved Pharmacological Profile for the Treatment of Cushing's DiseaseJuliette Emmerich, Chris J van Koppen, Jens L Burkhart, et al.European Journal of Medicinal Chemistry|July 23, 2024
Discovery and optimization of thiazole-based quorum sensing inhibitors as potent blockers of Pseudomonas aeruginosa pathogenicityAhmed S Abdelsamie, Mostafa M Hamed, Christian Schütz, et al.Natural Product Communications|March 4, 2011
Facile synthesis of chrysin-derivatives with promising activities as aromatase inhibitorsHamdoon A Mohammed, Lalla A Ba, Torsten Burkholz, et al.Chemistry (Weinheim an Der Bergstrasse, Germany)|January 28, 2020
Cystobactamid 507: Concise Synthesis, Mode of Action, and Optimization toward More Potent AntibioticsWalid A M Elgaher, Mostafa M Hamed, Sascha Baumann, et al.Future Medicinal Chemistry|June 3, 2016
Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologiesChristine K Maurer, Martina Fruth, Martin Empting, et al.Journal of Lipid Research|April 24, 2014
The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosisStephan Laggai, Sonja M Kessler, Stefan Boettcher, et al.Angewandte Chemie (International Ed. in English)|November 11, 2021
Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB InhibitorsCansu Kaya, Isabell Walter, Samir Yahiaoui, et al.Journal of the American Chemical Society|September 21, 2012
Validation of PqsD as an anti-biofilm target in Pseudomonas aeruginosa by development of small-molecule inhibitorsMichael P Storz, Christine K Maurer, Christina Zimmer, et al.Journal of Medicinal Chemistry|November 11, 2005
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approachAndrea Cavalli, Alessandra Bisi, Carlo Bertucci, et al.Pageof 26