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Expert Opinion on Drug Discovery
|
March 16, 2013
A structural biology view of target drugability
Ursula Egner, Roman C Hillig
The EMBO Journal
|
May 1, 2002
The complex of Arl2-GTP and PDE delta: from structure to function
Michael Hanzal-Bayer, Louis Renault, Pietro Roversi, et al.
Journal of Molecular Biology
|
April 24, 2007
Structural basis for a high affinity inhibitor bound to protein kinase MK2
Roman C Hillig, Uwe Eberspaecher, Felipe Monteclaro, et al.
The Journal of Biological Chemistry
|
September 24, 2002
HLA-B27 subtypes differentially associated with disease exhibit subtle structural alterations
Martin Hülsmeyer, Roman C Hillig, Armin Volz, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 28, 2015
Optimization of allosteric MEK inhibitors. Part 2: Taming the sulfamide group balances compound distribution properties
Ingo V Hartung, Stefanie Hammer, Marion Hitchcock, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
March 2, 2011
A crystallographic fragment screen identifies cinnamic acid derivatives as starting points for potent Pim-1 inhibitors
Michèle N Schulz, Jörg Fanghänel, Martina Schäfer, et al.
Acta Crystallographica. Section D, Structural Biology
|
November 17, 2025
Polo-like kinase 1-inhibitor co-complex structures via the surface-entropy reduction approach and a DARPin-assisted approach
Uwe Eberspaecher, Arndt A Schmitz, Gerhard Siemeister, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
March 3, 2007
Crystallization and molecular-replacement solution of a diagnostic fluorescent dye in complex with a specific Fab fragment
Roman C Hillig, Siegfried Baesler, Stefanie Urlinger, et al.
Chemmedchem
|
November 7, 2015
Modular Assembly of Allosteric MEK Inhibitor Structural Elements Unravels Potency and Feedback-Modulation Handles
Ingo V Hartung, Florian Pühler, Roland Neuhaus, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 18, 2004
Design and synthesis of macrocyclic inhibitors of phosphatase cdc25B
Stefan Bäurle, Thorsten Blume, Judith Günther, et al.
Page
of 3
Search research articles
Search
Showing results (1-10 of 30) with videos related to
Sort By:
Page
of 3
Expert Opinion on Drug Discovery
|
March 16, 2013
A structural biology view of target drugability
Ursula Egner, Roman C Hillig
The EMBO Journal
|
May 1, 2002
The complex of Arl2-GTP and PDE delta: from structure to function
Michael Hanzal-Bayer, Louis Renault, Pietro Roversi, et al.
Journal of Molecular Biology
|
April 24, 2007
Structural basis for a high affinity inhibitor bound to protein kinase MK2
Roman C Hillig, Uwe Eberspaecher, Felipe Monteclaro, et al.
The Journal of Biological Chemistry
|
September 24, 2002
HLA-B27 subtypes differentially associated with disease exhibit subtle structural alterations
Martin Hülsmeyer, Roman C Hillig, Armin Volz, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 28, 2015
Optimization of allosteric MEK inhibitors. Part 2: Taming the sulfamide group balances compound distribution properties
Ingo V Hartung, Stefanie Hammer, Marion Hitchcock, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
March 2, 2011
A crystallographic fragment screen identifies cinnamic acid derivatives as starting points for potent Pim-1 inhibitors
Michèle N Schulz, Jörg Fanghänel, Martina Schäfer, et al.
Acta Crystallographica. Section D, Structural Biology
|
November 17, 2025
Polo-like kinase 1-inhibitor co-complex structures via the surface-entropy reduction approach and a DARPin-assisted approach
Uwe Eberspaecher, Arndt A Schmitz, Gerhard Siemeister, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
March 3, 2007
Crystallization and molecular-replacement solution of a diagnostic fluorescent dye in complex with a specific Fab fragment
Roman C Hillig, Siegfried Baesler, Stefanie Urlinger, et al.
Chemmedchem
|
November 7, 2015
Modular Assembly of Allosteric MEK Inhibitor Structural Elements Unravels Potency and Feedback-Modulation Handles
Ingo V Hartung, Florian Pühler, Roland Neuhaus, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 18, 2004
Design and synthesis of macrocyclic inhibitors of phosphatase cdc25B
Stefan Bäurle, Thorsten Blume, Judith Günther, et al.
Page
of 3