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Cancer Discovery|June 3, 2023
SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted TherapyAlexander Drilon, Manish R Sharma, Melissa L Johnson, et al.ACS Medicinal Chemistry Letters|January 8, 2019
Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo ActivityJay B Fell, John P Fischer, Brian R Baer, et al.ACS Medicinal Chemistry Letters|December 18, 2014
C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase ActivatorsXiaohui Du, Ronald J Hinklin, Yumei Xiong, et al.Journal of Medicinal Chemistry|April 7, 2020
Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of CancerJay B Fell, John P Fischer, Brian R Baer, et al.Journal of Medicinal Chemistry|August 1, 2024
Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial EfficacyQuinn A Bumpers, Robert W Pipal, Anna M Benz-Weeden, et al.Pageof 2