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Blood|May 27, 2008
Cyproheptadine displays preclinical activity in myeloma and leukemiaXinliang Mao, Sheng-ben Liang, Rose Hurren, et al.Science Translational Medicine|April 10, 2020
The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viabilitySara Mirali, Aaron Botham, Veronique Voisin, et al.Leukemia|June 10, 2018
Preclinical evaluation of the selective small-molecule UBA1 inhibitor, TAK-243, in acute myeloid leukemiaSamir H Barghout, Parasvi S Patel, Xiaoming Wang, et al.Blood|April 17, 2020
Mitochondrial carrier homolog 2 is necessary for AML survivalDilshad H Khan, Michael Mullokandov, Yan Wu, et al.Nature Communications|February 17, 2021
Biological and therapeutic implications of a unique subtype of NPM1 mutated AMLArvind Singh Mer, Emily M Heath, Seyed Ali Madani Tonekaboni, et al.Cancer Research|August 15, 2008
Inhibition of the sodium/potassium ATPase impairs N-glycan expression and functionReza Beheshti Zavareh, Ken S Lau, Rose Hurren, et al.Leukemia|February 13, 2022
IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cellsBoaz Nachmias, Dilshad H Khan, Veronique Voisin, et al.American Journal of Hematology|November 26, 2013
Oral ciclopirox olamine displays biological activity in a phase I study in patients with advanced hematologic malignanciesMark D Minden, Donna E Hogge, Scott J Weir, et al.Blood|January 30, 2015
AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stressShrivani Sriskanthadevan, Danny V Jeyaraju, Timothy E Chung, et al.Leukemia Research|March 9, 2018
AML refractory to primary induction with Ida-FLAG has a poor clinical outcomeSimon Kavanagh, Emily Heath, Rose Hurren, et al.Pageof 7