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Frontiers in Molecular Biosciences|September 13, 2023
Optimization of a small molecule inhibitor of secondary nucleation in α-synuclein aggregationRoxine Staats, Z Faidon Brotzakis, Sean Chia, et al.
Iscience|September 16, 2024
HSPB6: A lipid-dependent molecular chaperone inhibits α-synuclein aggregationValentina Secco, Tatiana Tiago, Roxine Staats, et al.
ACS Chemical Biology|September 28, 2021
The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase ActivityKonrad J Mostert, Nandini Sharma, Marianne van der Zwaag, et al.
Communications Chemistry|January 27, 2023
Screening of small molecules using the inhibition of oligomer formation in α-synuclein aggregation as a selection parameterRoxine Staats, Thomas C T Michaels, Patrick Flagmeier, et al.
Molecular Pharmaceutics|November 14, 2022
Structure-Based Discovery of Small-Molecule Inhibitors of the Autocatalytic Proliferation of α-Synuclein AggregatesSean Chia, Z Faidon Brotzakis, Robert I Horne, et al.
Chemical Science|December 22, 2022
An antibody scanning method for the detection of α-synuclein oligomers in the serum of Parkinson's disease patientsKlara Kulenkampff, Derya Emin, Roxine Staats, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 25, 2025
Global kinetic model of lipid-induced <i>α</i>-synuclein aggregation and its inhibition by small moleculesAlisdair Stevenson, Roxine Staats, Alexander J Dear, et al.
Biochemistry|August 9, 2022
N-Terminal Acetylation of α-Synuclein Slows down Its Aggregation Process and Alters the Morphology of the Resulting AggregatesRosie Bell, Rebecca J Thrush, Marta Castellana-Cruz, et al.
Nature Chemical Biology|April 17, 2024
Discovery of potent inhibitors of α-synuclein aggregation using structure-based iterative learningRobert I Horne, Ewa A Andrzejewska, Parvez Alam, et al.
Frontiers in Neuroscience|July 5, 2021
Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their OligomersRyan Limbocker, Roxine Staats, Sean Chia, et al.
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