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The Journal of Biological Chemistry|January 22, 2026
BMI1 represses G-quadruplex DNA formation to maintain genomic stability during replicationRoy Hanna, Eric Deneault, Gilbert Bernier
Nature Communications|March 24, 2021
G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer's diseaseRoy Hanna, Anthony Flamier, Andrea Barabino, et al.
Iscience|March 28, 2025
Pharmaceutical inhibition of the Chk2 kinase mitigates cone photoreceptor degeneration in an iPSC model of Bardet-Biedl syndromeAndrea Barabino, Alisar Katbe, Roy Hanna, et al.
The Journal of Biological Chemistry|October 16, 2015
The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic CellsMohamed Abdouh, Roy Hanna, Jida El Hajjar, et al.
Stem Cell Reports|March 12, 2020
Deregulation of Neuro-Developmental Genes and Primary Cilium Cytoskeleton Anomalies in iPSC Retinal Sheets from Human Syndromic CiliopathiesAndrea Barabino, Anthony Flamier, Roy Hanna, et al.
NPJ Precision Oncology|January 15, 2020
Off-target effect of the BMI1 inhibitor PTC596 drives epithelial-mesenchymal transition in glioblastoma multiformeAnthony Flamier, Mohamed Abdouh, Rimi Hamam, et al.
Development (Cambridge, England)|November 26, 2025
Epigenomic alterations and neural development anomalies in induced pluripotent stem cells from sporadic Alzheimer's diseaseAlisar Katbe, Roy Hanna, Anthony Flamier, et al.
Development (Cambridge, England)|December 5, 2024
Molecular characterization and sub-retinal transplantation of hypoimmunogenic human retinal sheets in a minipig model of severe photoreceptor degenerationAndrea Barabino, Katia Mellal, Rimi Hamam, et al.
Scientific Reports|January 26, 2019
Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- miceJida El Hajjar, Wassim Chatoo, Roy Hanna, et al.
Development (Cambridge, England)|March 12, 2016
Loss of Bmi1 causes anomalies in retinal development and degeneration of cone photoreceptorsAndrea Barabino, Vicky Plamondon, Mohamed Abdouh, et al.
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