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Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 28, 2006
Comparison of mouse and rat cytochrome P450-mediated metabolism in liver and intestineMarcella Martignoni, Geny Groothuis, Ruben de KanterChemico-Biological Interactions|January 24, 2007
Induction of drug metabolizing enzymes: a survey of in vitro methodologies and interpretations used in the pharmaceutical industry--do they comply with FDA recommendations?Nicola J Hewitt, Ruben de Kanter, Edward LeCluyseExpert Opinion on Drug Metabolism & Toxicology|November 28, 2006
Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and inductionMarcella Martignoni, Geny M M Groothuis, Ruben de KanterCancer Chemotherapy and Pharmacology|December 14, 2004
Lack of strain-related differences in drug metabolism and efflux transporter characteristics between CD-1 and athymic nude miceMarcella Martignoni, Ruben de Kanter, Anna Moscone, et al.Toxicology in Vitro : an International Journal Published in Association with BIBRA|November 25, 2003
Phase I and phase II metabolic activities are retained in liver slices from mouse, rat, dog, monkey and human after cryopreservationMarcella Martignoni, Mario Monshouwer, Ruben de Kanter, et al.Chemico-Biological Interactions|December 21, 2004
An in vivo and in vitro comparison of CYP induction in rat liver and intestine using slices and quantitative RT-PCRMarcella Martignoni, Ruben de Kanter, Pietro Grossi, et al.Toxicology|September 20, 2005
An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobioticsLuisella Vignati, Elisa Turlizzi, Sonia Monaci, et al.Toxicology in Vitro : an International Journal Published in Association with BIBRA|August 16, 2005
An in vivo and in vitro comparison of CYP gene induction in mice using liver slices and quantitative RT-PCRMarcella Martignoni, Ruben de Kanter, Pietro Grossi, et al.Antimicrobial Agents and Chemotherapy|November 26, 2014
First-in-humans study of the safety, tolerability, and pharmacokinetics of ACT-451840, a new chemical entity with antimalarial activityShirin Bruderer, Noémie Hurst, Ruben de Kanter, et al.The Journal of Pharmacology and Experimental Therapeutics|April 29, 2014
Macitentan does not interfere with hepatic bile salt transportAlexander Treiber, Päivi Äänismaa, Ruben de Kanter, et al.Pageof 4