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Clinical Pharmacokinetics|September 20, 2015
Physiologically-Based Pharmacokinetic Modeling of Macitentan: Prediction of Drug-Drug InteractionsRuben de Kanter, Patricia N Sidharta, Stéphane Delahaye, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|July 25, 2017
The metabolism and drug-drug interaction potential of the selective prostacyclin receptor agonist selexipagCarmela Gnerre, Jérôme Segrestaa, Swen Seeland, et al.
Molecular Pharmacology|December 6, 2017
S1P<sub>1</sub> Modulator-Induced G <i></i><sub>i</sub> Signaling and <i>β</i>-Arrestin Recruitment Are Both Necessary to Induce Rapid and Efficient Reduction of Blood Lymphocyte Count In VivoMagdalena Birker-Robaczewska, Martin Bolli, Markus Rey, et al.
The Journal of Pharmacology and Experimental Therapeutics|July 1, 2017
The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468Alexander Treiber, Ruben de Kanter, Catherine Roch, et al.
Pharmacogenomics|April 6, 2016
Assessment of drug metabolism enzyme and transporter pharmacogenetics in drug discovery and early development: perspectives of the I-PWGWilliam Brian, Larry M Tremaine, Million Arefayene, et al.
Bioorganic & Medicinal Chemistry Letters|December 25, 2012
Novel in vivo active anti-malarials based on a hydroxy-ethyl-amine scaffoldClaire-Lise Ciana, Romain Siegrist, Hamed Aissaoui, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 18, 2006
Empirical validation of a rat in vitro organ slice model as a tool for in vivo clearance predictionInge A M de Graaf, Ruben de Kanter, Marina H de Jager, et al.
European Journal of Medicinal Chemistry|March 31, 2016
Novel S1P1 receptor agonists - Part 5: From amino-to alkoxy-pyridinesMartin H Bolli, Cyrille Lescop, Magdalena Birker, et al.
Nature Protocols|August 21, 2010
Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studiesInge A M de Graaf, Peter Olinga, Marina H de Jager, et al.
European Journal of Medicinal Chemistry|April 11, 2016
Novel S1P1 receptor agonists - Part 4: Alkylaminomethyl substituted aryl head groupsCyrille Lescop, Claus Müller, Boris Mathys, et al.
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