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Genome Biology|October 5, 2010
Rat traps: filling the toolbox for manipulating the rat genomeRuben van Boxtel, Edwin Cuppen
Methods in Molecular Biology (Clifton, N.J.)|November 17, 2010
Generation of genetically modified rodents using random ENU mutagenesisRuben van Boxtel, Edwin Cuppen
Genome Medicine|April 27, 2018
MutationalPatterns: comprehensive genome-wide analysis of mutational processesFrancis Blokzijl, Roel Janssen, Ruben van Boxtel, et al.
BMC Cancer|May 17, 2019
Portrait of a cancer: mutational signature analyses for cancer diagnosticsArne Van Hoeck, Niels H Tjoonk, Ruben van Boxtel, et al.
Methods in Molecular Biology (Clifton, N.J.)|December 17, 2009
ENU mutagenesis to generate genetically modified rat modelsRuben van Boxtel, Michael N Gould, Edwin Cuppen, et al.
Nature Methods|October 19, 2010
Mutation discovery by targeted genomic enrichment of multiplexed barcoded samplesIsaäc J Nijman, Michal Mokry, Ruben van Boxtel, et al.
The American Journal of Pathology|August 23, 2011
Homozygous and heterozygous p53 knockout rats develop metastasizing sarcomas with high frequencyRuben van Boxtel, Raoul V Kuiper, Pim W Toonen, et al.
Proceedings of the National Academy of Sciences of the United States of America|December 15, 2017
Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidneyFrans Schutgens, Maarten B Rookmaaker, Francis Blokzijl, et al.
Nature Protocols|December 8, 2017
Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid culturesMyrthe Jager, Francis Blokzijl, Valentina Sasselli, et al.
BMC Genomics|October 9, 2008
Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animalsRuben van Boxtel, Pim W Toonen, Mark Verheul, et al.
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