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International Journal of Molecular Sciences|January 10, 2026
Structural Communication Between C-Peptide and Insulin Within the Proinsulin MoleculeRubing Shao, Maroof Alam, Leena Haataja, et al.Diabetes|August 31, 2021
Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced DiabetesMaroof Alam, Anoop Arunagiri, Leena Haataja, et al.The Journal of Biological Chemistry|August 21, 2022
Proteasomal degradation of WT proinsulin in pancreatic beta cellsXiaoxi Xu, Anoop Arunagiri, Leena Haataja, et al.Diabetes|January 30, 2016
Disulfide Mispairing During Proinsulin Folding in the Endoplasmic ReticulumLeena Haataja, Nandini Manickam, Ann Soliman, et al.Clinical Diabetes and Endocrinology|July 14, 2017
Hyperglucagonemia in an animal model of insulin- deficient diabetes: what therapy can improve it?Fabrizio Barbetti, Carlo Colombo, Leena Haataja, et al.Nature Communications|October 14, 2021
PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormonesYu-Jie Chen, Jeffrey Knupp, Anoop Arunagiri, et al.Autophagy|November 15, 2021
The ER transmembrane protein PGRMC1 recruits misfolded proteins for reticulophagic clearanceJeffrey Knupp, Yu-Jie Chen, Anoop Arunagiri, et al.The Journal of Biological Chemistry|May 20, 2023
Nutrient-dependent regulation of β-cell proinsulin contentXiaoxi Xu, Anoop Arunagiri, Maroof Alam, et al.The Journal of Clinical Investigation|January 19, 2021
Normal and defective pathways in biogenesis and maintenance of the insulin storage poolMing Liu, Yumeng Huang, Xiaoxi Xu, et al.The Journal of Clinical Investigation|June 1, 2013
Dominant protein interactions that influence the pathogenesis of conformational diseasesJordan Wright, Xiaofan Wang, Leena Haataja, et al.Pageof 36