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Drug Development Research|May 15, 2025
Augmenting the Anti-Leukemic Activity of the BCL-2 Inhibitor Venetoclax Through Its Transformation Into Polypharmacologic Dual BCL-2/HDAC1 and Dual BCL-2/HDAC6 InhibitorsAlexandria M Chan, Christian Eberly, Brandon Drennen, et al.
The Laryngoscope|May 21, 2013
The effect of geniglossal advancement on airway flow using a computational flow dynamics modelAaron Fletcher, Jiwoong Choi, Maged Awadalla, et al.
Chemmedchem|July 1, 2014
Discovery of methyl 4'-methyl-5-(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)-[1,1'-biphenyl]-3-carboxylate, an improved small-molecule inhibitor of c-Myc-max dimerizationJay Chauhan, Huabo Wang, Jeremy L Yap, et al.
Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons|June 23, 2025
What Factors Influence Success of Mandibular Reconstructions With Patient-Specific Selective Laser Melted Reconstruction Plates?Jeffrey S Marschall, Mitchell Frerichs, Thomas Keith, et al.
European Journal of Medicinal Chemistry|January 15, 2025
The polypharmacy combination of the BCL-2 inhibitor venetoclax (VEN) and the FLT3 inhibitor gilteritinib (GIL) is more active in acute myeloid leukemia cells than novel polypharmacologic BCL-2/FLT3 VEN-GIL hybrid single-molecule inhibitorsChristopher C Goodis, Christian Eberly, Alexandria M Chan, et al.
Drug Design, Development and Therapy|February 28, 2020
Optimization of a Benzothiazole Indolene Scaffold Targeting Bacterial Cell Wall AssemblyJay Chauhan, Wenbo Yu, Steven Cardinale, et al.
RSC Medicinal Chemistry|September 12, 2022
Scaffold hopping from indoles to indazoles yields dual MCL-1/BCL-2 inhibitors from MCL-1 selective leadsBrandon Drennen, Christopher C Goodis, Nathan Bowen, et al.
Biochemical and Biophysical Research Communications|January 25, 2017
CG13250, a novel bromodomain inhibitor, suppresses proliferation of multiple myeloma cells in an orthotopic mouse modelNatsuki Imayoshi, Makoto Yoshioka, Jay Chauhan, et al.
Nucleic Acid Therapeutics|May 27, 2026
Unraveling the Stereochemical Complexity of Phosphorothioate-Modified Oligonucleotides Using Analytical TechnologiesAkanksha Manghrani, Maharshi C Patel, Frank Delaglio, et al.
Chemmedchem|June 26, 2020
Rationally Designed Polypharmacology: α-Helix Mimetics as Dual Inhibitors of the Oncoproteins Mcl-1 and HDM2Ivie L Conlon, Brandon Drennen, Maryanna E Lanning, et al.
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