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The Journal of Pharmacology and Experimental Therapeutics|October 28, 2020
Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative StressRamon Martinez, Weiliang Huang, Ramin Samadani, et al.Organic & Biomolecular Chemistry|March 8, 2012
Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitorsJeremy L Yap, Xiaobo Cao, Kenno Vanommeslaeghe, et al.Bioorganic & Medicinal Chemistry Letters|November 29, 2016
Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - A novel class of compounds with potent activity against acute myeloid leukemia cellsBrandon A Carter-Cooper, Steven Fletcher, Dana Ferraris, et al.Chemical Communications (Cambridge, England)|January 29, 2010
Coordination complex SH2 domain proteomimetics: an alternative approach to disrupting oncogenic protein-protein interactionsJoel A Drewry, Steven Fletcher, Peibin Yue, et al.Journal of Medicinal Chemistry|December 14, 2011
Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activityBrent D G Page, Haytham Khoury, Rob C Laister, et al.ACS Medicinal Chemistry Letters|January 14, 2026
First-in-Class Potent, Dual HDAC6/Proteasome Inhibitors Lacking a Hydroxamic Acid Motif: Discovery of Novel Anti-Multiple Myeloma AgentsAlexandria M Chan, Brandon D Lowe, Andrea L Cottingham, et al.BMC Cancer|November 23, 2012
The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibitionChander Peddaboina, Daniel Jupiter, Steven Fletcher, et al.Bioorganic & Medicinal Chemistry Letters|April 30, 2018
Kröhnke pyridines: Rapid and facile access to Mcl-1 inhibitorsIvie L Conlon, Daniel Van Eker, Sameh Abdelmalak, et al.Biodiversity Data Journal|August 3, 2017
A global map of saltmarshesChris J Mcowen, Lauren V Weatherdon, Jan-Willem Van Bochove, et al.Bioorganic & Medicinal Chemistry Letters|January 14, 2018
Discovery of Mcl-1 inhibitors based on a thiazolidine-2,4-dione scaffoldEllis Whiting, Mithun R Raje, Jay Chauhan, et al.Pageof 11