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Aging Cell|October 27, 2023
A comprehensive AI-driven analysis of large-scale omic datasets reveals novel dual-purpose targets for the treatment of cancer and agingFrank W Pun, Geoffrey Ho Duen Leung, Hoi Wing Leung, et al.
Aging|April 3, 2025
Decreased mitochondrial NAD+ in WRN deficient cells links to dysfunctional proliferationSofie Lautrup, Shi-Qi Zhang, Shinichiro Funayama, et al.
EMBO Molecular Medicine|October 15, 2025
Isoginkgetin antagonizes ALS pathologies in its animal and patient iPSC models via PINK1-Parkin-dependent mitophagyAng Li, Sen Huang, Shu-Qin Cao, et al.
Nature Neuroscience|February 12, 2019
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's diseaseEvandro F Fang, Yujun Hou, Konstantinos Palikaras, et al.
Aging|August 30, 2022
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summaryTomas Schmauck-Medina, Adrian Molière, Sofie Lautrup, et al.
Brain : a Journal of Neurology|August 24, 2021
Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathwayYalun Zhang, Yi Zhang, Yahyah Aman, et al.
The Journal of Clinical Investigation|November 21, 2022
Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patientsLeiv Otto Watne, Christian Thomas Pollmann, Bjørn Erik Neerland, et al.
Progress in Neurobiology|September 22, 2023
TRPM2 as a conserved gatekeeper determines the vulnerability of DA neurons by mediating ROS sensing and calcium dyshomeostasisPeiwu Ye, Qiuyuan Fang, Xupang Hu, et al.
Scientific Reports|April 12, 2017
Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathwayEvandro F Fang, Tyler B Waltz, Henok Kassahun, et al.
Journal of Immunology (Baltimore, Md. : 1950)|January 24, 2016
Critical Role of Antimicrobial Peptide Cathelicidin for Controlling Helicobacter pylori Survival and InfectionLin Zhang, William K K Wu, Richard L Gallo, et al.
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