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Bioorganic & Medicinal Chemistry Letters
|
December 24, 2018
Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout
Jing-Wei Wu, Ling Yin, Yu-Qiang Liu, et al.
Journal of Computer-Aided Molecular Design
|
July 14, 2019
Structure based design of selective SHP2 inhibitors by De novo design, synthesis and biological evaluation
Wen-Shan Liu, Wen-Yan Jin, Liang Zhou, et al.
Combinatorial Chemistry & High Throughput Screening
|
June 19, 2016
Identification of Novel PPARα/γ Dual Agonists by Virtual Screening of Specs Database
Jun Zhang, Xin Liu, Shu-Qing Wang, et al.
Journal of Biomolecular Structure & Dynamics
|
July 2, 2019
Investigating the reason for loss-of-function of Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) caused by Y279C mutation through molecular dynamics simulation
Wen-Shan Liu, Rui-Rui Wang, Wei-Ya Li, et al.
Journal of Molecular Graphics & Modelling
|
September 11, 2021
Molecular dynamics study of CDC25B<sup>R492L</sup> mutant causing the activity decrease of CDC25B
Hao-Xin Li, Wen-Yu Yang, Li-Peng Li, et al.
Journal of Biomolecular Structure & Dynamics
|
October 8, 2019
Identification of potential leukocyte antigen-related protein (PTP-LAR) inhibitors through 3D QSAR pharmacophore-based virtual screening and molecular dynamics simulation
Shan Du, Bing Yang, Xin Wang, et al.
Chemical Biology & Drug Design
|
July 16, 2013
Design and synthesis of imidazolidine-2,4-dione derivatives as selective inhibitors by targeting protein tyrosine phosphatase-1B over T-cell protein tyrosine phosphatase
Ying Ma, Su-Xia Sun, Xian-Chao Cheng, et al.
Combinatorial Chemistry & High Throughput Screening
|
November 1, 2014
Design novel inhibitors for treating cancer by targeting Cdc25B catalytic domain with de novo design
Jing-Wei Wu, Huan Zhang, Yu-Qing Duan, et al.
Chemical Biology & Drug Design
|
January 15, 2014
The discovery of a novel and selective inhibitor of PTP1B over TCPTP: 3D QSAR pharmacophore modeling, virtual screening, synthesis, and biological evaluation
Ying Ma, Yuan-Yuan Jin, Ye-Liu Wang, et al.
Bioorganic Chemistry
|
October 28, 2020
Scaffold-based selective SHP2 inhibitors design using core hopping, molecular docking, biological evaluation and molecular simulation
Wei-Ya Li, Ying Ma, Hao-Xin Li, et al.
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Showing results (31-40 of 57) with videos related to
Sort By:
Page
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Bioorganic & Medicinal Chemistry Letters
|
December 24, 2018
Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout
Jing-Wei Wu, Ling Yin, Yu-Qiang Liu, et al.
Journal of Computer-Aided Molecular Design
|
July 14, 2019
Structure based design of selective SHP2 inhibitors by De novo design, synthesis and biological evaluation
Wen-Shan Liu, Wen-Yan Jin, Liang Zhou, et al.
Combinatorial Chemistry & High Throughput Screening
|
June 19, 2016
Identification of Novel PPARα/γ Dual Agonists by Virtual Screening of Specs Database
Jun Zhang, Xin Liu, Shu-Qing Wang, et al.
Journal of Biomolecular Structure & Dynamics
|
July 2, 2019
Investigating the reason for loss-of-function of Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) caused by Y279C mutation through molecular dynamics simulation
Wen-Shan Liu, Rui-Rui Wang, Wei-Ya Li, et al.
Journal of Molecular Graphics & Modelling
|
September 11, 2021
Molecular dynamics study of CDC25B<sup>R492L</sup> mutant causing the activity decrease of CDC25B
Hao-Xin Li, Wen-Yu Yang, Li-Peng Li, et al.
Journal of Biomolecular Structure & Dynamics
|
October 8, 2019
Identification of potential leukocyte antigen-related protein (PTP-LAR) inhibitors through 3D QSAR pharmacophore-based virtual screening and molecular dynamics simulation
Shan Du, Bing Yang, Xin Wang, et al.
Chemical Biology & Drug Design
|
July 16, 2013
Design and synthesis of imidazolidine-2,4-dione derivatives as selective inhibitors by targeting protein tyrosine phosphatase-1B over T-cell protein tyrosine phosphatase
Ying Ma, Su-Xia Sun, Xian-Chao Cheng, et al.
Combinatorial Chemistry & High Throughput Screening
|
November 1, 2014
Design novel inhibitors for treating cancer by targeting Cdc25B catalytic domain with de novo design
Jing-Wei Wu, Huan Zhang, Yu-Qing Duan, et al.
Chemical Biology & Drug Design
|
January 15, 2014
The discovery of a novel and selective inhibitor of PTP1B over TCPTP: 3D QSAR pharmacophore modeling, virtual screening, synthesis, and biological evaluation
Ying Ma, Yuan-Yuan Jin, Ye-Liu Wang, et al.
Bioorganic Chemistry
|
October 28, 2020
Scaffold-based selective SHP2 inhibitors design using core hopping, molecular docking, biological evaluation and molecular simulation
Wei-Ya Li, Ying Ma, Hao-Xin Li, et al.
Page
of 6