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Journal of Medicinal Chemistry|June 9, 2006
Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activityBruce G Szczepankiewicz, Christi Kosogof, Lissa T J Nelson, et al.Journal of Medicinal Chemistry|June 9, 2006
Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitorsZhonghua Pei, Xiaofeng Li, Kenton Longenecker, et al.Journal of Medicinal Chemistry|October 13, 2006
Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]- 4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279): a very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetesDavid J Madar, Hana Kopecka, Daisy Pireh, et al.Journal of Medicinal Chemistry|June 26, 2024
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C InhibitorXiaoshen Ma, David L Sloman, Ruchia Duggal, et al.Bioorganic & Medicinal Chemistry Letters|May 15, 2017
Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammationGraham F Smith, Michael D Altman, Brian Andresen, et al.Pageof 6