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Nature Communications|July 6, 2026
The H3K4 methyltransferase KMT2D is an essential cofactor for GATA1 at erythroid gene enhancersJianxiang Zhang, Ye Xin, Li Cheng, et al.Blood|November 5, 2025
Silencing of BCL11A by Disrupting Enhancer-Dependent Epigenetic InsulationKaili Wang, Juan Wang, Ruopeng Feng, et al.Cell Reports|January 12, 2022
SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemiaSofya A Polyanskaya, Rosamaria Y Moreno, Bin Lu, et al.Nature|October 12, 2022
Activation of γ-globin expression by hypoxia-inducible factor 1αRuopeng Feng, Thiyagaraj Mayuranathan, Peng Huang, et al.Nature Communications|July 27, 2025
Removal of promoter CpG methylation by epigenome editing reverses HBG silencingHenry W Bell, Ruopeng Feng, Manan Shah, et al.Nature Genetics|May 26, 2022
Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cellsKunhua Qin, Peng Huang, Ruopeng Feng, et al.Molecular Cell|December 10, 2020
ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin ExpressionXianjiang Lan, Ren Ren, Ruopeng Feng, et al.Blood Advances|July 31, 2023
ETV6 represses inflammatory response genes and regulates HSPC function during stress hematopoiesis in miceMackenzie Bloom, Ninad Oak, Rebekah Baskin-Doerfler, et al.Blood|November 6, 2020
FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesisPeng Xu, Daniel C Scott, Beisi Xu, et al.Nature Genetics|July 3, 2023
Potent and uniform fetal hemoglobin induction via base editingThiyagaraj Mayuranathan, Gregory A Newby, Ruopeng Feng, et al.Pageof 3