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Bioorganic & Medicinal Chemistry Letters
|
August 30, 2008
Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase
Frank Ruebsam, Zhongxiang Sun, Benjamin K Ayida, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 5, 2008
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine
Yuefen Zhou, Stephen E Webber, Douglas E Murphy, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
January 16, 2024
Phase I Study of ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer Progressing on Enzalutamide
Wassim Abida, Andrew W Hahn, Neal Shore, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 30, 2008
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones: Part 4. Optimization of DMPK properties
Maria V Sergeeva, Yuefen Zhou, Darian M Bartkowski, et al.
Cancer Discovery
|
November 30, 2018
A Phase I/Ib Trial of the VEGFR-Sparing Multikinase RET Inhibitor RXDX-105
Alexander Drilon, Siqing Fu, Manish R Patel, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 20, 2008
Pyrrolo[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase
Frank Ruebsam, Stephen E Webber, Martin T Tran, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 7, 2008
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 3: Further optimization of the 2-, 6-, and 7'-substituents and initial pharmacokinetic assessments
Lian-Sheng Li, Yuefen Zhou, Douglas E Murphy, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 17, 2008
Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase
Sun Hee Kim, Martin T Tran, Frank Ruebsam, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 30, 2008
4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase
David A Ellis, Julie K Blazel, Stephen E Webber, et al.
Cancer Research
|
November 6, 2025
Enozertinib is a Selective, Brain-penetrant EGFR inhibitor for Treating Non-small Cell Lung Cancers with EGFR Exon 20 and Atypical Mutations
Melissa R Junttila, Claire E Repellin, Sumeet Salaniwal, et al.
Page
of 9
Search research articles
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Showing results (71-80 of 82) with videos related to
Sort By:
Page
of 9
Bioorganic & Medicinal Chemistry Letters
|
August 30, 2008
Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase
Frank Ruebsam, Zhongxiang Sun, Benjamin K Ayida, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 5, 2008
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine
Yuefen Zhou, Stephen E Webber, Douglas E Murphy, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
January 16, 2024
Phase I Study of ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer Progressing on Enzalutamide
Wassim Abida, Andrew W Hahn, Neal Shore, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 30, 2008
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones: Part 4. Optimization of DMPK properties
Maria V Sergeeva, Yuefen Zhou, Darian M Bartkowski, et al.
Cancer Discovery
|
November 30, 2018
A Phase I/Ib Trial of the VEGFR-Sparing Multikinase RET Inhibitor RXDX-105
Alexander Drilon, Siqing Fu, Manish R Patel, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 20, 2008
Pyrrolo[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase
Frank Ruebsam, Stephen E Webber, Martin T Tran, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 7, 2008
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 3: Further optimization of the 2-, 6-, and 7'-substituents and initial pharmacokinetic assessments
Lian-Sheng Li, Yuefen Zhou, Douglas E Murphy, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 17, 2008
Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase
Sun Hee Kim, Martin T Tran, Frank Ruebsam, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 30, 2008
4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase
David A Ellis, Julie K Blazel, Stephen E Webber, et al.
Cancer Research
|
November 6, 2025
Enozertinib is a Selective, Brain-penetrant EGFR inhibitor for Treating Non-small Cell Lung Cancers with EGFR Exon 20 and Atypical Mutations
Melissa R Junttila, Claire E Repellin, Sumeet Salaniwal, et al.
Page
of 9