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Journal of Lipid Research|March 20, 2020
Schnyder corneal dystrophy-associated UBIAD1 is defective in MK-4 synthesis and resists autophagy-mediated degradationDong-Jae Jun, Marc M Schumacher, Seonghwan Hwang, et al.
Nature Communications|July 25, 2022
Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domainHongwen Chen, Xiaofeng Qi, Rebecca A Faulkner, et al.
The Journal of Biological Chemistry|April 22, 2010
Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid dropletsIsamu Z Hartman, Pingsheng Liu, John K Zehmer, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 15, 2025
Allosteric regulation of UBIAD1 trafficking from ER to Golgi revealed by chemical genetic screeningDong-Jae Jun, Marc M Schumacher, Youngah Jo, et al.
The Journal of Nutrition|September 22, 2021
Multiple Dietary Vitamin K Forms Are Converted to Tissue Menaquinone-4 in MiceJessie L Ellis, Xueyan Fu, J Philip Karl, et al.
Experimental Biology and Medicine (Maywood, N.J.)|September 6, 2013
Geranylgeraniol suppresses the viability of human DU145 prostate carcinoma cells and the level of HMG CoA reductaseNicolle V Fernandes, Hoda Yeganehjoo, Rajasekhar Katuru, et al.
The Journal of Biological Chemistry|May 1, 2016
Contribution of Accelerated Degradation to Feedback Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Metabolism in the LiverSeonghwan Hwang, Isamu Z Hartman, Leona N Calhoun, et al.
Cell Metabolism|August 8, 2007
Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductaseJian Cao, Jiang Wang, Wei Qi, et al.
Elife|March 3, 2020
Enhanced ER-associated degradation of HMG CoA reductase causes embryonic lethality associated with Ubiad1 deficiencyYoungah Jo, Steven S Kim, Kristina Garland, et al.
Elife|February 21, 2019
Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in miceYoungah Jo, Jason S Hamilton, Seonghwan Hwang, et al.
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