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Cancer Research|December 7, 2007
Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivoJi-Liang Li, Richard C A Sainson, Wen Shi, et al.Journal of Oncology|July 24, 2010
Effects of HIF-1alpha and HIF2alpha on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 XenograftsSwethajit Biswas, Helen Troy, Russell Leek, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|August 24, 2013
The G-protein-coupled receptor CLR is upregulated in an autocrine loop with adrenomedullin in clear cell renal cell carcinoma and associated with poor prognosisLeonid L Nikitenko, Russell Leek, Stephen Henderson, et al.Blood|June 19, 2010
New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomesHelen Sheldon, Emily Heikamp, Helen Turley, et al.Molecular Cancer Research : MCR|August 5, 2021
ADGRL4/ELTD1 Expression in Breast Cancer Cells Induces Vascular Normalization and Immune SuppressionHelen Sheldon, Esther Bridges, Ildefonso Silva, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|April 14, 2012
Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapyAlan McIntyre, Shalini Patiar, Simon Wigfield, et al.Journal of Molecular Medicine (Berlin, Germany)|January 31, 2013
Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenograftsKrishan Kumar, Simon Wigfield, Harriet E Gee, et al.Carcinogenesis|July 11, 2012
CD31 angiogenesis and combined expression of HIF-1α and HIF-2α are prognostic in primary clear-cell renal cell carcinoma (CC-RCC), but HIFα transcriptional products are not: implications for antiangiogenic trials and HIFα biomarker studies in primary CC-RCCSwethajit Biswas, Philip J S Charlesworth, Gareth D H Turner, et al.The American Journal of Pathology|February 20, 2010
Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancerAdrian M Jubb, Elizabeth J Soilleux, Helen Turley, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|March 1, 2015
A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid TumorsElena Gabriela Chiorean, Patricia LoRusso, Robert Matthew Strother, et al.Pageof 4