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Ruth Brenk

Showing results (41-50 of 65) with videos related to

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Plos One|November 30, 2018
In silico identification and experimental validation of hits active against KPC-2 β-lactamaseRaphael Klein, Pasquale Linciano, Giuseppe Celenza, et al.
Chemistry & Biology|March 29, 2011
Novel ligands for a purine riboswitch discovered by RNA-ligand dockingPeter Daldrop, Francis E Reyes, David A Robinson, et al.
Bioorganic & Medicinal Chemistry Letters|September 12, 2006
Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sicknessMichael D Urbaniak, Jioji N Tabudravu, Aichi Msaki, et al.
Chemmedchem|June 30, 2021
An Experimental Toolbox for Structure-Based Hit Discovery for P. aeruginosa FabF, a Promising Target for AntibioticsLudvik Olai Espeland, Charis Georgiou, Raphael Klein, et al.
Journal of Medicinal Chemistry|March 27, 2009
A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapyNicola L Ramsden, Lori Buetow, Alice Dawson, et al.
Journal of Medicinal Chemistry|March 21, 2003
Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysisRuth Brenk, Lars Naerum, Ulrich Grädler, et al.
ACS Chemical Biology|March 29, 2013
De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragmentsRobert Urich, Grant Wishart, Michael Kiczun, et al.
Journal of Medicinal Chemistry|February 17, 2006
Design, synthesis, and biological evaluation of 3,4-diarylmaleimides as angiogenesis inhibitorsChristian Peifer, Thomas Stoiber, Eberhard Unger, et al.
Communications Chemistry|January 25, 2023
Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97Sebastian Bothe, Petra Hänzelmann, Stephan Böhler, et al.
Journal of Chemical Information and Modeling|January 26, 2024
Investigating Polypharmacology through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3Parveen Gartan, Fahimeh Khorsand, Pushpak Mizar, et al.
Pageof 7

Showing results (41-50 of 65) with videos related to

Sort By:
Pageof 7
Plos One|November 30, 2018
In silico identification and experimental validation of hits active against KPC-2 β-lactamaseRaphael Klein, Pasquale Linciano, Giuseppe Celenza, et al.
Chemistry & Biology|March 29, 2011
Novel ligands for a purine riboswitch discovered by RNA-ligand dockingPeter Daldrop, Francis E Reyes, David A Robinson, et al.
Bioorganic & Medicinal Chemistry Letters|September 12, 2006
Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sicknessMichael D Urbaniak, Jioji N Tabudravu, Aichi Msaki, et al.
Chemmedchem|June 30, 2021
An Experimental Toolbox for Structure-Based Hit Discovery for P. aeruginosa FabF, a Promising Target for AntibioticsLudvik Olai Espeland, Charis Georgiou, Raphael Klein, et al.
Journal of Medicinal Chemistry|March 27, 2009
A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapyNicola L Ramsden, Lori Buetow, Alice Dawson, et al.
Journal of Medicinal Chemistry|March 21, 2003
Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysisRuth Brenk, Lars Naerum, Ulrich Grädler, et al.
ACS Chemical Biology|March 29, 2013
De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragmentsRobert Urich, Grant Wishart, Michael Kiczun, et al.
Journal of Medicinal Chemistry|February 17, 2006
Design, synthesis, and biological evaluation of 3,4-diarylmaleimides as angiogenesis inhibitorsChristian Peifer, Thomas Stoiber, Eberhard Unger, et al.
Communications Chemistry|January 25, 2023
Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97Sebastian Bothe, Petra Hänzelmann, Stephan Böhler, et al.
Journal of Chemical Information and Modeling|January 26, 2024
Investigating Polypharmacology through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3Parveen Gartan, Fahimeh Khorsand, Pushpak Mizar, et al.
Pageof 7