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The Journal of Pharmacology and Experimental Therapeutics|September 26, 2009
Benzodiazepine binding site occupancy by the novel GABAA receptor subtype-selective drug 7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) in rats, primates, and humansJohn R Atack, Dean F Wong, Tim D Fryer, et al.Journal of Medicinal Chemistry|June 25, 2004
Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and analogues as subtype-selective inverse agonists for the GABA(A)alpha5 benzodiazepine binding siteLeslie J Street, Francine Sternfeld, Richard A Jelley, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|November 18, 2005
Evidence for a significant role of alpha 3-containing GABAA receptors in mediating the anxiolytic effects of benzodiazepinesRebecca Dias, Wayne F A Sheppard, Rosa L Fradley, et al.The Journal of Pharmacology and Experimental Therapeutics|August 26, 2009
In vitro and in vivo properties of 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA receptor alpha5 subtype-selective inverse agonistJohn R Atack, Karen A Maubach, Keith A Wafford, et al.Pageof 3