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Methods in Molecular Biology (Clifton, N.J.)|August 25, 2021
Mechanistic and Structural Features of PROTAC Ternary ComplexesRyan Casement, Adam Bond, Conner Craigon, et al.Nature Communications|October 10, 2023
Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2Sarath Ramachandran, Nikolai Makukhin, Kevin Haubrich, et al.Nature Chemical Biology|November 4, 2022
Functional E3 ligase hotspots and resistance mechanisms to small-molecule degradersAlexander Hanzl, Ryan Casement, Hana Imrichova, et al.Journal of Medicinal Chemistry|September 14, 2023
Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α StabilizersLan Phuong Vu, Claudia J Diehl, Ryan Casement, et al.Nature Chemical Biology|May 12, 2026
Dual E3 ligase recruitment by monovalent degraders for tunable SMARCA 2/4 degradationValentina A Spiteri, Dmitri Segal, Alejandro Correa-Sáez, et al.Nature|February 21, 2024
Targeted protein degradation via intramolecular bivalent gluesOliver Hsia, Matthias Hinterndorfer, Angus D Cowan, et al.Pageof 1