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Methods in Molecular Biology (Clifton, N.J.)|August 25, 2021
Mechanistic and Structural Features of PROTAC Ternary ComplexesRyan Casement, Adam Bond, Conner Craigon, et al.Bioorganic & Medicinal Chemistry Letters|March 8, 2022
Targeting epigenetic modulators using PROTAC degraders: Current status and future perspectiveThomas Webb, Conner Craigon, Alessio CiulliJournal of Medicinal Chemistry|December 9, 2021
Amide-to-Ester Substitution as a Strategy for Optimizing PROTAC Permeability and Cellular ActivityVictoria G Klein, Adam G Bond, Conner Craigon, et al.Science Advances|October 11, 2024
Mechanism of degrader-targeted protein ubiquitinabilityCharlotte Crowe, Mark A Nakasone, Sarah Chandler, et al.Journal of Medicinal Chemistry|October 15, 2021
Development of BromoTag: A "Bump-and-Hole"-PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target ProteinsAdam G Bond, Conner Craigon, Kwok-Ho Chan, et al.Methods in Molecular Biology (Clifton, N.J.)|June 5, 2013
Biophysical screening for the discovery of small-molecule ligandsAlessio CiulliNature|February 21, 2024
Targeted protein degradation via intramolecular bivalent gluesOliver Hsia, Matthias Hinterndorfer, Angus D Cowan, et al.Nature Communications|October 10, 2023
Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2Sarath Ramachandran, Nikolai Makukhin, Kevin Haubrich, et al.Nature Chemical Biology|November 4, 2022
Functional E3 ligase hotspots and resistance mechanisms to small-molecule degradersAlexander Hanzl, Ryan Casement, Hana Imrichova, et al.Current Opinion in Structural Biology|January 29, 2017
Recognition of substrate degrons by E3 ubiquitin ligases and modulation by small-molecule mimicry strategiesXavier Lucas, Alessio CiulliPageof 15