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Pharmacology & Therapeutics|April 1, 2023
ORMDL in metabolic health and diseaseRyan D R Brown, Sarah Spiegel
Journal of Lipid Research|May 8, 2024
ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesisRyan D R Brown, Usha Mahawar, Binks W Wattenberg, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|May 31, 2022
A new preclinical model of western diet-induced progression of non-alcoholic steatohepatitis to hepatocellular carcinomaChristopher D Green, Cynthia Weigel, Ryan D R Brown, et al.
Cell Biochemistry and Biophysics|May 15, 2021
Dihydroceramide Desaturase Functions as an Inducer and Rectifier of Apoptosis: Effect of Retinol Derivatives, Antioxidants and Phenolic CompoundsMariam Alsanafi, Ryan D R Brown, Jeongah Oh, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|August 10, 2024
FTY720/Fingolimod mitigates paclitaxel-induced Sparcl1-driven neuropathic pain and breast cancer progressionSandeep K Singh, Cynthia Weigel, Ryan D R Brown, et al.
Biorxiv : the Preprint Server for Biology|November 24, 2025
Depot-specific roles for sphingosine kinase 1 in conversion of white adipose to thermogenic adiposeYolander Valentine, Maryam Jamil, Anna Kovilakath, et al.
Molecular Metabolism|June 26, 2024
Sphingosine kinase 2 and p62 regulation are determinants of sexual dimorphism in hepatocellular carcinomaChristopher D Green, Ryan D R Brown, Baasanjav Uranbileg, et al.
Molecular Metabolism|December 11, 2023
Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitisRyan D R Brown, Christopher D Green, Cynthia Weigel, et al.
Biorxiv : the Preprint Server for Biology|October 4, 2023
The sterol transporter STARD3 transports sphingosine at ER-lysosome contact sitesPia Hempelmann, Fabio Lolicato, Andrea Graziadei, et al.
The Journal of Biological Chemistry|April 18, 2021
A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cellsRyan D R Brown, Ben E P Veerman, Jeongah Oh, et al.
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