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Bioconjugate Chemistry|January 22, 2025
5'-Amino-Formyl-Thieno[3,2-b]thiophene End-Label for On-Strand Synthesis of Far-Red Fluorescent Molecular Rotors and pH-Responsive ProbesRyan E Johnson, Keenan T Regan, Richard A Manderville
Chemical Research in Toxicology|February 6, 2025
A High-Affinity and Selective DNA Aptamer for the N-Linked C8-Deoxyguanosine Adduct Produced by the Arylamine Carcinogen 4-AminobiphenylYijing Chen, Ryan E Johnson, Richard A Manderville, et al.
Bioconjugate Chemistry|September 20, 2021
On-Strand Knoevenagel Insertion of a Hemicyanine Molecular Rotor Loop Residue for Turn-On Fluorescence Detection of Pb-Induced G-Quadruplex RigidityRyan E Johnson, Abigail J Van Riesen, Richard A Manderville
ACS Sensors|February 26, 2025
Harnessing a Fluorescent Nucleobase Surrogate for Supramolecular FRET-Aptamer Detection and Target-Site MappingKarley J L Zimmer, Ryan E Johnson, Hunter Little, et al.
Chemical Science|May 14, 2023
A modular aldol approach for internal fluorescent molecular rotor chalcone surrogates for DNA biosensing applicationsRyan E Johnson, Makay T Murray, Lucas J Bycraft, et al.
Bioconjugate Chemistry|October 19, 2023
Harnessing a 4-Formyl-Aniline Handle to Tune the Stability of a DNA Aptamer-Protein Complex via Fluorescent SurrogatesRyan E Johnson, Makay T Murray, Lucas J Bycraft, et al.
The Journal of Organic Chemistry|December 28, 2020
Temperature Sensing of Thiolate Addition by Phenolate Merocyanine Dyes: Importance of the Quinone Methide Resonance StructureAbigail J Van Riesen, Ryan E Johnson, M Sameer Al-Abdul-Wahid, et al.
Chemical Science|March 19, 2025
Modular access to nucleobase GFP-surrogates: pH-responsive smart probes for ratiometric nucleic acid diagnosticsKeenan T Regan, Austin Pounder, Ryan E Johnson, et al.
Journal of the American Chemical Society|October 13, 2025
Cleavable Hydrophobic Anchors Optimize Immunomodulatory Effects of OligonucleotidesTaokun Luo, Young Jun Kim, Alex Cushing, et al.
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