Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Ryan J Watts

Showing results (51-60 of 74) with videos related to

Pageof 8
Sort By:
Journal of Alzheimer'S Disease : JAD|January 21, 2017
A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease BrainsPatrick C G Haddick, Jessica L Larson, Nisha Rathore, et al.
Journal of Medicinal Chemistry|November 21, 2014
8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitorsAllen A Thomas, Kevin W Hunt, Brad Newhouse, et al.
Nature Medicine|November 25, 2014
A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell deathMonica K Wetzel-Smith, Julie Hunkapiller, Tushar R Bhangale, et al.
Nature|July 18, 2012
A mutation in APP protects against Alzheimer's disease and age-related cognitive declineThorlakur Jonsson, Jasvinder K Atwal, Stacy Steinberg, et al.
Journal of Medicinal Chemistry|March 30, 2013
Spirocyclic β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid β in a higher speciesKevin W Hunt, Adam W Cook, Ryan J Watts, et al.
British Journal of Pharmacology|September 1, 2017
Widespread brain distribution and activity following i.c.v. infusion of anti-β-secretase (BACE1) in nonhuman primatesDaniela Bumbaca Yadav, Janice A Maloney, Kristin R Wildsmith, et al.
Journal of Medicinal Chemistry|January 9, 2014
Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous systemAllen A Thomas, Kevin W Hunt, Matthew Volgraf, et al.
The Journal of Clinical Investigation|March 31, 2018
Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulationFan Liao, Aimin Li, Monica Xiong, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 17, 2009
VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesisFan Zhang, Zhongshu Tang, Xu Hou, et al.
Neuron|January 7, 2020
TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic ChallengeAlicia A Nugent, Karin Lin, Bettina van Lengerich, et al.
Pageof 8

Showing results (51-60 of 74) with videos related to

Sort By:
Pageof 8
Journal of Alzheimer'S Disease : JAD|January 21, 2017
A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease BrainsPatrick C G Haddick, Jessica L Larson, Nisha Rathore, et al.
Journal of Medicinal Chemistry|November 21, 2014
8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitorsAllen A Thomas, Kevin W Hunt, Brad Newhouse, et al.
Nature Medicine|November 25, 2014
A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell deathMonica K Wetzel-Smith, Julie Hunkapiller, Tushar R Bhangale, et al.
Nature|July 18, 2012
A mutation in APP protects against Alzheimer's disease and age-related cognitive declineThorlakur Jonsson, Jasvinder K Atwal, Stacy Steinberg, et al.
Journal of Medicinal Chemistry|March 30, 2013
Spirocyclic β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid β in a higher speciesKevin W Hunt, Adam W Cook, Ryan J Watts, et al.
British Journal of Pharmacology|September 1, 2017
Widespread brain distribution and activity following i.c.v. infusion of anti-β-secretase (BACE1) in nonhuman primatesDaniela Bumbaca Yadav, Janice A Maloney, Kristin R Wildsmith, et al.
Journal of Medicinal Chemistry|January 9, 2014
Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous systemAllen A Thomas, Kevin W Hunt, Matthew Volgraf, et al.
The Journal of Clinical Investigation|March 31, 2018
Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulationFan Liao, Aimin Li, Monica Xiong, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 17, 2009
VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesisFan Zhang, Zhongshu Tang, Xu Hou, et al.
Neuron|January 7, 2020
TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic ChallengeAlicia A Nugent, Karin Lin, Bettina van Lengerich, et al.
Pageof 8