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International Journal of Molecular Sciences
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November 20, 2020
Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers
Ryan P Kreiser, Aidan K Wright, Natalie R Block, et al.
ACS Chemical Neuroscience
|
February 28, 2024
A Relationship between the Structures and Neurotoxic Effects of Aβ Oligomers Stabilized by Different Metal Ions
Sean Chia, Rodrigo Lessa Cataldi, Francesco Simone Ruggeri, et al.
Chemico-Biological Interactions
|
December 19, 2022
EGCG inactivates a pore-forming toxin by promoting its oligomerization and decreasing its solvent-exposed hydrophobicity
Justus M Gabriel, Thomas Tan, Dillon J Rinauro, et al.
Journal of the American Chemical Society
|
May 14, 2026
Glucagon-Like Peptide-1 Receptor Agonists Inhibit the Initiation of Toxic Amyloid-β42 Aggregation
Lucas B Fallot, Carol A Anderson, Johnathan R Pinc, et al.
Scientific Reports
|
September 18, 2020
A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer's disease
Tatsuya Ikenoue, Francesco A Aprile, Pietro Sormanni, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 25, 2016
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease
Johnny Habchi, Sean Chia, Ryan Limbocker, et al.
Journal of Medicinal Chemistry
|
July 11, 2023
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes
Silvia Errico, Giacomo Lucchesi, Davide Odino, et al.
International Journal of Molecular Sciences
|
July 8, 2020
Rationally Designed Antibodies as Research Tools to Study the Structure-Toxicity Relationship of Amyloid-β Oligomers
Ryan Limbocker, Benedetta Mannini, Rodrigo Cataldi, et al.
Science Advances
|
November 5, 2020
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease
Gabriella T Heller, Francesco A Aprile, Thomas C T Michaels, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
June 5, 2020
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers
Francesco A Aprile, Pietro Sormanni, Marina Podpolny, et al.
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Search research articles
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Showing results (11-20 of 30) with videos related to
Sort By:
Page
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International Journal of Molecular Sciences
|
November 20, 2020
Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers
Ryan P Kreiser, Aidan K Wright, Natalie R Block, et al.
ACS Chemical Neuroscience
|
February 28, 2024
A Relationship between the Structures and Neurotoxic Effects of Aβ Oligomers Stabilized by Different Metal Ions
Sean Chia, Rodrigo Lessa Cataldi, Francesco Simone Ruggeri, et al.
Chemico-Biological Interactions
|
December 19, 2022
EGCG inactivates a pore-forming toxin by promoting its oligomerization and decreasing its solvent-exposed hydrophobicity
Justus M Gabriel, Thomas Tan, Dillon J Rinauro, et al.
Journal of the American Chemical Society
|
May 14, 2026
Glucagon-Like Peptide-1 Receptor Agonists Inhibit the Initiation of Toxic Amyloid-β42 Aggregation
Lucas B Fallot, Carol A Anderson, Johnathan R Pinc, et al.
Scientific Reports
|
September 18, 2020
A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer's disease
Tatsuya Ikenoue, Francesco A Aprile, Pietro Sormanni, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 25, 2016
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease
Johnny Habchi, Sean Chia, Ryan Limbocker, et al.
Journal of Medicinal Chemistry
|
July 11, 2023
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes
Silvia Errico, Giacomo Lucchesi, Davide Odino, et al.
International Journal of Molecular Sciences
|
July 8, 2020
Rationally Designed Antibodies as Research Tools to Study the Structure-Toxicity Relationship of Amyloid-β Oligomers
Ryan Limbocker, Benedetta Mannini, Rodrigo Cataldi, et al.
Science Advances
|
November 5, 2020
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease
Gabriella T Heller, Francesco A Aprile, Thomas C T Michaels, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
June 5, 2020
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers
Francesco A Aprile, Pietro Sormanni, Marina Podpolny, et al.
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of 3